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KIF5B and POLR2G
Data Source:
BioGRID
(two hybrid)
KIF5B
POLR2G
Description
kinesin family member 5B
RNA polymerase II subunit G
Image
GO Annotations
Cellular Component
Cytosol
Kinesin Complex
Microtubule
Membrane
Vesicle
Dendrite Cytoplasm
Centriolar Satellite
Ciliary Rootlet
Axonal Growth Cone
Phagocytic Vesicle
Perinuclear Region Of Cytoplasm
Axon Cytoplasm
P-body
Nucleus
Nucleoplasm
RNA Polymerase II, Core Complex
Molecular Function
Microtubule Motor Activity
Protein Binding
ATP Binding
Microtubule Binding
JUN Kinase Binding
ATP-dependent Microtubule Motor Activity, Plus-end-directed
ATPase Activity
Identical Protein Binding
Cadherin Binding
Microtubule Lateral Binding
Single-stranded DNA Binding
Single-stranded RNA Binding
DNA-directed 5'-3' RNA Polymerase Activity
Protein Binding
Translation Initiation Factor Binding
Biological Process
Microtubule-based Movement
Cytoplasm Organization
Axon Guidance
Hippocampus Development
Cytoskeleton-dependent Intracellular Transport
Positive Regulation Of Vesicle Fusion
Positive Regulation Of Synaptic Transmission, GABAergic
Stress Granule Disassembly
Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Regulation Of Membrane Potential
Positive Regulation Of Potassium Ion Transport
Vesicle Transport Along Microtubule
Synaptic Vesicle Transport
Centrosome Localization
Cellular Response To Interferon-gamma
Plus-end-directed Vesicle Transport Along Microtubule
Positive Regulation Of Intracellular Protein Transport
Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex
Anterograde Axonal Protein Transport
Positive Regulation Of Protein Localization To Plasma Membrane
Positive Regulation Of Voltage-gated Sodium Channel Activity
Anterograde Neuronal Dense Core Vesicle Transport
Retrograde Neuronal Dense Core Vesicle Transport
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic
MRNA Splicing, Via Spliceosome
Transcription-coupled Nucleotide-excision Repair
Transcription, DNA-templated
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Apoptotic Process
Fibroblast Growth Factor Receptor Signaling Pathway
RNA Metabolic Process
Somatic Stem Cell Population Maintenance
SnRNA Transcription By RNA Polymerase II
Positive Regulation Of Translational Initiation
Positive Regulation Of Viral Transcription
Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening
Regulation Of Gene Silencing By MiRNA
Pathways
MHC class II antigen presentation
Insulin processing
RHO GTPases activate KTN1
COPI-dependent Golgi-to-ER retrograde traffic
Kinesins
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Viral Messenger RNA Synthesis
MicroRNA (miRNA) biogenesis
Transcriptional regulation by small RNAs
PIWI-interacting RNA (piRNA) biogenesis
Activation of anterior HOX genes in hindbrain development during early embryogenesis
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Signaling by FGFR2 IIIa TM
Estrogen-dependent gene expression
Inhibition of DNA recombination at telomere
Drugs
Diseases
GWAS
Anti-saccade response (
29064472
)
Bipolar disorder with mood-incongruent psychosis (
23092984
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Glycine levels (
30837465
)
Pulse pressure (
27841878
)
Systolic blood pressure (
27841878
)
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Interacting Genes
36 interacting genes:
APC
BAG4
CCDC136
CDC5L
CDR2
DTNB
FHL2
GCC1
GSK3B
HSF2BP
KIF5A
KLC3
KTN1
LBX1
MEOX2
MYO5A
NCOA2
NDRG1
POLR2G
POU6F2
PRKAR1B
PRKAR2B
RAPGEF2
RRBP1
SNAP23
SNAP25
SUMO2
SYBU
TAX1BP1
VPS52
YWHAB
YWHAG
YWHAH
YWHAQ
YWHAZ
ZBTB8A
46 interacting genes:
ATF7IP
BCL2L15
C22orf15
CIB3
CNTNAP2
DDX54
DES
DUSP29
EIF3D
EIF4A3
EWSR1
FNDC4
FOSL2
GPKOW
HOXC5
KIF5B
LMO2
MAPK1
MCM3AP
MCPH1
MYOD1
NOTCH2NLA
NTRK2
OSGIN1
PARVG
POLR1C
POLR2A
POLR2C
POLR2D
POLR2E
POLR2F
POLR2H
POLR2K
POLR2L
PRKRA
PSMB8
STK19
TAF15
TNNC1
TRAPPC2L
TRIM14
TRIM68
TSEN15
UPRT
VHL
ZNF410
Entrez ID
3799
5436
HPRD ID
07214
15995
Ensembl ID
ENSG00000170759
ENSG00000168002
Uniprot IDs
P33176
Q6P164
V9HW29
P62487
PDB IDs
1BG2
1MKJ
2P4N
3J8X
3J8Y
4HNA
4LNU
5LT0
5LT1
5LT2
5LT3
5LT4
6OJQ
2C35
5IY6
5IY7
5IY8
5IY9
5IYA
5IYB
5IYC
5IYD
6DRD
6O9L
Enriched GO Terms of Interacting Partners
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