KIF5B and RRBP1

Data Source:
HPRD (two hybrid, in vitro)

		KIF5B	RRBP1
Description		kinesin family member 5B	ribosome binding protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Kinesin Complex Microtubule Membrane Vesicle Dendrite Cytoplasm Centriolar Satellite Ciliary Rootlet Axonal Growth Cone Phagocytic Vesicle Perinuclear Region Of Cytoplasm Axon Cytoplasm	Endoplasmic Reticulum Ribosome Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding JUN Kinase Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Identical Protein Binding Cadherin Binding Microtubule Lateral Binding	RNA Binding Signaling Receptor Activity
	Biological Process	Microtubule-based Movement Cytoplasm Organization Axon Guidance Hippocampus Development Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Vesicle Fusion Positive Regulation Of Synaptic Transmission, GABAergic Stress Granule Disassembly Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulation Of Membrane Potential Positive Regulation Of Potassium Ion Transport Vesicle Transport Along Microtubule Synaptic Vesicle Transport Centrosome Localization Cellular Response To Interferon-gamma Plus-end-directed Vesicle Transport Along Microtubule Positive Regulation Of Intracellular Protein Transport Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex Anterograde Axonal Protein Transport Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Voltage-gated Sodium Channel Activity Anterograde Neuronal Dense Core Vesicle Transport Retrograde Neuronal Dense Core Vesicle Transport	Osteoblast Differentiation Translation Protein Transport
Pathways		MHC class II antigen presentation Insulin processing RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs			Radezolid
Diseases
GWAS		Anti-saccade response ( 29064472) Bipolar disorder with mood-incongruent psychosis ( 23092984) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Glycine levels ( 30837465) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Apolipoprotein A1 levels ( 32203549) Coronary artery disease ( 29212778) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Frontotemporal dementia (age at onset) ( 29724592) Frontotemporal dementia with GRN mutation (age at onset) ( 29724592) HDL cholesterol levels ( 32203549) Height ( 31562340) Platelet count ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		36 interacting genes: APC BAG4 CCDC136 CDC5L CDR2 DTNB FHL2 GCC1 GSK3B HSF2BP KIF5A KLC3 KTN1 LBX1 MEOX2 MYO5A NCOA2 NDRG1 POLR2G POU6F2 PRKAR1B PRKAR2B RAPGEF2 RRBP1 SNAP23 SNAP25 SUMO2 SYBU TAX1BP1 VPS52 YWHAB YWHAG YWHAH YWHAQ YWHAZ ZBTB8A	4 interacting genes: ATF7IP KIF5B PRKD2 SMAD9
Entrez ID		3799	6238
HPRD ID		07214	11796
Ensembl ID		ENSG00000170759	ENSG00000125844
Uniprot IDs		P33176 Q6P164 V9HW29	Q9P2E9
PDB IDs		1BG2 1MKJ 2P4N 3J8X 3J8Y 4HNA 4LNU 5LT0 5LT1 5LT2 5LT3 5LT4 6OJQ
Enriched GO Terms of Interacting Partners?
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