HNRNPC and KPNA5

Data Source:
BioGRID (two hybrid)

		HNRNPC	KPNA5
Description		heterogeneous nuclear ribonucleoprotein C	karyopherin subunit alpha 5
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GO Annotations	Cellular Component	Chromatin Extracellular Region Nucleus Nucleoplasm Spliceosomal Complex Telomerase Holoenzyme Complex Cytosol Actin Cytoskeleton Membrane Protein-containing Complex Extracellular Exosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Cytosol
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Protein Binding Poly(U) RNA Binding Nucleosomal DNA Binding Identical Protein Binding Telomerase RNA Binding N6-methyladenosine-containing RNA Binding	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity
	Biological Process	MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Splicing RNA Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase ATP-dependent Chromatin Remodeling 3'-UTR-mediated MRNA Stabilization	NLS-bearing Protein Import Into Nucleus Modulation By Virus Of Host Cellular Process
Pathways		SUMOylation of RNA binding proteins mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756 21738484) Height ( 31562340)	Early cardiac repolarization ( 31600170) Telomere length ( 21460395)
Interacting Genes		58 interacting genes: AP1M1 BARD1 BRCA1 BRCA2 BRIP1 BTRC CCDC85B CDKN2A CSNK1A1 CSNK2A1 CSNK2A2 DHX9 DISC1 EPS8 ERG ESR1 FAS FXR2 GRB2 HNRNPCL1 HNRNPCL2 IL7R KHDRBS3 KPNA2 KPNA3 KPNA4 KPNA5 KRAS LMO2 LMO3 MEOX2 PALB2 PAX6 PDGFB PHKB PIN1 PJA1 PRKDC PTBP2 RAD51 RALY RALYL RBM41 RBPMS2 RNF4 SDCBP SF3B2 SMARCD1 SREK1 SRPK2 SUMO1 SUMO1P1 TRAF3 UBE2I YWHAE YWHAQ ZFYVE26 ZNF581	28 interacting genes: ANP32A ANP32B ARNT BRMS1 CDKN1B DCPS EPAS1 FAM214B FBXO7 HIF1A HNRNPC IL32 KAT5 LMNB1 MLH1 NMNAT1 NRF1 NUP50 POLR3C POU6F2 RAD52 RBBP4 SPOP SPOPL TSEN54 TWIST1 WT1 ZNF326
Entrez ID		3183	3841
HPRD ID		01243	05179
Ensembl ID		ENSG00000092199	ENSG00000196911
Uniprot IDs		P07910	O15131
PDB IDs		1TXP 1WF2 2MXY 2MZ1 3LN4	4U2X
Enriched GO Terms of Interacting Partners?
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