H2AC21 and WDR77

Data Source:
BioGRID (pull down)

		H2AC21	WDR77
Description		H2A clustered histone 21	WD repeat domain 77
Image		No pdb structure
GO Annotations	Cellular Component	Nucleosome Nucleus Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Methylosome Pole Plasm
	Molecular Function	Molecular_function DNA Binding Protein Binding Protein Heterodimerization Activity	Protein Binding Methyl-CpG Binding Nuclear Receptor Coactivator Activity
	Biological Process	Chromatin Silencing Biological_process	Spliceosomal SnRNP Assembly Regulation Of Transcription By RNA Polymerase II Pole Plasm Assembly Positive Regulation Of Cell Population Proliferation Positive Regulation Of Transcription, DNA-templated Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Pathways		HDACs deacetylate histones HATs acetylate histones HATs acetylate histones RMTs methylate histone arginines UCH proteinases Ub-specific processing proteases Metalloprotease DUBs HCMV Early Events HCMV Late Events	snRNP Assembly RMTs methylate histone arginines
Drugs
Diseases
GWAS
Interacting Genes		3 interacting genes: APP EP300 WDR77	44 interacting genes: AQR BAG2 CDK19 CDK8 CLNS1A CREBBP CTDP1 GLI1 GPKOW H2AC21 HNRNPM LSM3 NKX3-1 PCBP2 PPIL1 PPP1R8 PQBP1 PRKG1 PRKG2 PRMT5 QKI RBM5 RIOK1 SAP30BP SF1 SF3A1 SF3B4 SIRT7 SMAD1 SMYD1 SNRPB SNRPC SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SUZ12 THOC1 TOE1 YWHAB YWHAQ ZMYND19 ZNF207
Entrez ID		317772	79084
HPRD ID		13659	14387
Ensembl ID		ENSG00000184270	ENSG00000116455
Uniprot IDs		Q8IUE6	A0A024R0H7 Q9BQA1
PDB IDs			4GQB 4X60 4X61 4X63 5C9Z 5EMJ 5EMK 5EML 5EMM 5FA5 6CKC 6K1S 6RLL 6RLQ 6UXX 6UXY 6V0N 6V0O
Enriched GO Terms of Interacting Partners?
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