SLC29A2 and GJA4

Data Source:
BioGRID (two hybrid)

		SLC29A2	GJA4
Description		solute carrier family 29 member 2	gap junction protein alpha 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleolus Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Basolateral Plasma Membrane Nuclear Membrane Presynapse	Integral Component Of Plasma Membrane Gap Junction Connexin Complex
	Molecular Function	Neurotransmitter Transmembrane Transporter Activity Nucleoside Transmembrane Transporter Activity Purine Nucleoside Transmembrane Transporter Activity Uridine Transmembrane Transporter Activity	Gap Junction Channel Activity Protein Binding
	Biological Process	Neurotransmitter Uptake Neurotransmitter Transport Adenine Transport Guanine Transport Nucleoside Transport Purine Nucleoside Transmembrane Transport Uridine Transport Adenosine Transport Hypoxanthine Transport Thymine Transport Pyrimidine-containing Compound Transmembrane Transport Neurotransmitter Reuptake Transport Across Blood-brain Barrier Nucleoside Transmembrane Transport	Blood Vessel Development Endothelium Development Calcium Ion Transport Cell-cell Junction Assembly Cell-cell Signaling Response To Pain Transmembrane Transport
Pathways		Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	Gap junction assembly
Drugs		Ethanol
Diseases
GWAS		Bipolar disorder ( 21926972) Serum uric acid levels ( 32514006)	Formal thought disorder in schizophrenia ( 22648509) Triglyceride levels x thiazide or thiazide-like diuretics use interaction ( 31806883)
Interacting Genes		19 interacting genes: ALOX5AP CERS3 CERS4 CREB3 ERGIC3 GJA4 GPR152 LAPTM4B PLPP5 SERINC2 SLC10A1 SLC10A6 TMEM237 TMEM242 TMEM33 TMEM86B TMX2 UBQLN1 UBQLN2	5 interacting genes: CD81 MS4A13 OPRM1 SLC29A2 TMEM86B
Entrez ID		3177	2701
HPRD ID		03662	08509
Ensembl ID		ENSG00000174669	ENSG00000187513
Uniprot IDs		G5E943 Q14542 Q96FB2	P35212
PDB IDs
Enriched GO Terms of Interacting Partners?
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