ONECUT1 and FOXA1

Data Source:
BioGRID (pull down)

		ONECUT1	FOXA1
Description		one cut homeobox 1	forkhead box A1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Chromatin Fibrillar Center Nucleus Nucleoplasm Microvillus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Sequence-specific Double-stranded DNA Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Protein Domain Specific Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Liver Development Regulation Of Cell-matrix Adhesion Epithelial Cell Development Glucose Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Notch Signaling Pathway Endoderm Development Anatomical Structure Morphogenesis B Cell Differentiation Positive Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Endocrine Pancreas Development Cell Fate Commitment Positive Regulation Of Transcription By RNA Polymerase II Spleen Development Cilium Assembly	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Notch Signaling Pathway Anatomical Structure Morphogenesis Negative Regulation Of Epithelial To Mesenchymal Transition Dorsal/ventral Neural Tube Patterning Cell Differentiation Response To Estradiol Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Hormone Metabolic Process Glucose Homeostasis Positive Regulation Of Apoptotic Process Positive Regulation Of Neuron Differentiation Positive Regulation Of Smoothened Signaling Pathway Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Formation Involved In Morphogenesis Neuron Fate Specification Positive Regulation Of DNA-binding Transcription Factor Activity Epithelial Tube Branching Involved In Lung Morphogenesis Lung Epithelial Cell Differentiation Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Epithelial-mesenchymal Signaling Involved In Prostate Gland Development Prostate Gland Epithelium Morphogenesis Prostate Gland Stromal Morphogenesis Epithelial Cell Maturation Involved In Prostate Gland Development Alveolar Secondary Septum Development Dopaminergic Neuron Differentiation Respiratory Basal Cell Differentiation Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin
Pathways		Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells Regulation of gene expression in early pancreatic precursor cells	Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Adult body size ( 32376654) Birth weight ( 31043758) C-reactive protein levels ( 30388399) Chronotype ( 30696823) Lead levels ( 26025379) Metabolite levels ( 23823483) Telomere length ( 29151059) Type 2 diabetes ( 30297969)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergy ( 27182965) Chromium levels ( 26025379) Coronary artery aneurysm in Kawasaki disease ( 26434682) Diastolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415) Intraocular pressure ( 29617998) Periodontitis (CDC/AAP) ( 24024966) Self-reported allergy ( 23817569) Tonsillectomy ( 27182965 28928442)
Interacting Genes		5 interacting genes: CREBBP FOXA1 FOXA2 KAT2B NR3C1	6 interacting genes: AR H3-4 NKX2-1 ONECUT1 SEZ6L2 TLE1
Entrez ID		3175	3169
HPRD ID		05002	03801
Ensembl ID		ENSG00000169856	ENSG00000129514
Uniprot IDs		Q9UBC0	P55317
PDB IDs
Enriched GO Terms of Interacting Partners?
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