FOXA1 and SEZ6L2

Data Source:
BioGRID (two hybrid)

		FOXA1	SEZ6L2
Description		forkhead box A1	seizure related 6 homolog like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Fibrillar Center Nucleus Nucleoplasm Microvillus	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Protein Domain Specific Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Notch Signaling Pathway Anatomical Structure Morphogenesis Negative Regulation Of Epithelial To Mesenchymal Transition Dorsal/ventral Neural Tube Patterning Cell Differentiation Response To Estradiol Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Hormone Metabolic Process Glucose Homeostasis Positive Regulation Of Apoptotic Process Positive Regulation Of Neuron Differentiation Positive Regulation Of Smoothened Signaling Pathway Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Formation Involved In Morphogenesis Neuron Fate Specification Positive Regulation Of DNA-binding Transcription Factor Activity Epithelial Tube Branching Involved In Lung Morphogenesis Lung Epithelial Cell Differentiation Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Epithelial-mesenchymal Signaling Involved In Prostate Gland Development Prostate Gland Epithelium Morphogenesis Prostate Gland Stromal Morphogenesis Epithelial Cell Maturation Involved In Prostate Gland Development Alveolar Secondary Septum Development Dopaminergic Neuron Differentiation Respiratory Basal Cell Differentiation Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin
Pathways		Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergy ( 27182965) Chromium levels ( 26025379) Coronary artery aneurysm in Kawasaki disease ( 26434682) Diastolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415) Intraocular pressure ( 29617998) Periodontitis (CDC/AAP) ( 24024966) Self-reported allergy ( 23817569) Tonsillectomy ( 27182965 28928442)	Alcohol consumption ( 31358974) Alcohol consumption (drinks per week) ( 30643258) Anthropometric traits ( 19260139) Autism spectrum disorder or schizophrenia ( 28540026) Bitter alcoholic beverage consumption ( 31046077) Body fat distribution (arm fat ratio) ( 30664634) Response to taxane treatment (placlitaxel) ( 23006423) Schizophrenia ( 28991256 25056061 29483656) Systemic lupus erythematosus ( 23273568)
Interacting Genes		6 interacting genes: AR H3-4 NKX2-1 ONECUT1 SEZ6L2 TLE1	7 interacting genes: ETV5 FOXA1 MTDH OASL TK1 TOX3 UNG
Entrez ID		3169	26470
HPRD ID		03801	06686
Ensembl ID		ENSG00000129514	ENSG00000174938
Uniprot IDs		P55317	A0A087WYL5 A0A0A8K8P7 B7Z5L4 Q6UXD5
PDB IDs
Enriched GO Terms of Interacting Partners?
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