FOXA1 and ONECUT1

Data Source:
BioGRID (pull down)

		FOXA1	ONECUT1
Description		forkhead box A1	one cut homeobox 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Fibrillar Center Nucleus Nucleoplasm Microvillus	Chromatin Nucleus
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Protein Domain Specific Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Notch Signaling Pathway Anatomical Structure Morphogenesis Negative Regulation Of Epithelial To Mesenchymal Transition Dorsal/ventral Neural Tube Patterning Cell Differentiation Response To Estradiol Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Hormone Metabolic Process Glucose Homeostasis Positive Regulation Of Apoptotic Process Positive Regulation Of Neuron Differentiation Positive Regulation Of Smoothened Signaling Pathway Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Formation Involved In Morphogenesis Neuron Fate Specification Positive Regulation Of DNA-binding Transcription Factor Activity Epithelial Tube Branching Involved In Lung Morphogenesis Lung Epithelial Cell Differentiation Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Epithelial-mesenchymal Signaling Involved In Prostate Gland Development Prostate Gland Epithelium Morphogenesis Prostate Gland Stromal Morphogenesis Epithelial Cell Maturation Involved In Prostate Gland Development Alveolar Secondary Septum Development Dopaminergic Neuron Differentiation Respiratory Basal Cell Differentiation Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin	Liver Development Regulation Of Cell-matrix Adhesion Epithelial Cell Development Glucose Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Notch Signaling Pathway Endoderm Development Anatomical Structure Morphogenesis B Cell Differentiation Positive Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Endocrine Pancreas Development Cell Fate Commitment Positive Regulation Of Transcription By RNA Polymerase II Spleen Development Cilium Assembly
Pathways		Estrogen-dependent gene expression	Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells Regulation of gene expression in early pancreatic precursor cells
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergy ( 27182965) Chromium levels ( 26025379) Coronary artery aneurysm in Kawasaki disease ( 26434682) Diastolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415) Intraocular pressure ( 29617998) Periodontitis (CDC/AAP) ( 24024966) Self-reported allergy ( 23817569) Tonsillectomy ( 27182965 28928442)	Adult body size ( 32376654) Birth weight ( 31043758) C-reactive protein levels ( 30388399) Chronotype ( 30696823) Lead levels ( 26025379) Metabolite levels ( 23823483) Telomere length ( 29151059) Type 2 diabetes ( 30297969)
Interacting Genes		6 interacting genes: AR H3-4 NKX2-1 ONECUT1 SEZ6L2 TLE1	5 interacting genes: CREBBP FOXA1 FOXA2 KAT2B NR3C1
Entrez ID		3169	3175
HPRD ID		03801	05002
Ensembl ID		ENSG00000129514	ENSG00000169856
Uniprot IDs		P55317	Q9UBC0
PDB IDs
Enriched GO Terms of Interacting Partners?
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