MTERF3 and RHBDD2

Data Source:
BioGRID (two hybrid)

		MTERF3	RHBDD2
Description		mitochondrial transcription termination factor 3	rhomboid domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Cytosol	Golgi Membrane Hrd1p Ubiquitin Ligase ERAD-L Complex Nucleoplasm Golgi Apparatus Integral Component Of Endoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding	Serine-type Endopeptidase Activity Misfolded Protein Binding Ubiquitin-specific Protease Binding
	Biological Process	Macroautophagy Negative Regulation Of Transcription, DNA-templated Mitochondrial Ribosome Assembly	Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response
Pathways		PINK1-PRKN Mediated Mitophagy
Drugs
Diseases
GWAS			Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Neutrophil percentage of granulocytes ( 27863252) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		28 interacting genes: ADGRE2 AGTRAP APOC1 APP ARL6IP1 CACFD1 CMTM5 ERG28 FADS6 FUNDC1 GPR108 HIGD1C MAL2 MIR34B PBX3 RHBDD2 SCAMP1 SLC17A9 SLC2A5 SLC50A1 STX8 SYNGR1 SYP TMEM14C UPF2 YIF1A ZDHHC21 ZFPL1	58 interacting genes: ABHD16A ACSF2 ADORA2A BCL2L1 BCL2L2 CCR9 CHRM4 CIAO2A CIDEB COL8A1 COMT DIABLO DRD2 DYNC1H1 ERBB2 FKBP8 FMO4 GAL3ST3 GCSH GDF5-AS1 H2BC3 H4C7 IFI27L1 IL32 LETMD1 LIG4 MAOB MFSD14C MICOS13 MIEF2 MLX MMRN2 MPC2 MRM1 MRPL35 MTERF3 MYG1 NAALAD2 NCBP2AS2 NFU1 NRM PBX3 PTAFR ROMO1 RSAD2 SCGB3A1 SDHD SLC25A2 SLC25A3 SNPH SYT16 TEX44 THBD TIMM17B TPRG1 TSR1 TUFM USP30
Entrez ID		51001	57414
HPRD ID		10823	11492
Ensembl ID		ENSG00000156469	ENSG00000005486
Uniprot IDs		E5RIK9 Q96E29	Q6NTF9
PDB IDs		3M66
Enriched GO Terms of Interacting Partners?
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