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HDGF and XBP1
Data Source:
BioGRID
(two hybrid)
HDGF
XBP1
Description
heparin binding growth factor
X-box binding protein 1
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Nucleus
Nucleoplasm
Cytoplasm
Transcription Repressor Complex
Collagen-containing Extracellular Matrix
Nucleus
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Molecular Function
Nucleotide Binding
Transcription Corepressor Binding
Double-stranded DNA Binding
Transcription Coregulator Activity
Transcription Corepressor Activity
RNA Binding
Growth Factor Activity
Heparin Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Cis-regulatory Region Sequence-specific DNA Binding
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Protein Heterodimerization Activity
Sequence-specific Double-stranded DNA Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Signal Transduction
IRE1-mediated Unfolded Protein Response
Cellular Response To Interleukin-7
Angiogenesis
Liver Development
Positive Regulation Of Immunoglobulin Production
Transcription By RNA Polymerase II
Ubiquitin-dependent Protein Catabolic Process
Fatty Acid Biosynthetic Process
Autophagy
Apoptotic Process
Immune Response
Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response
Muscle Organ Development
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Myotube Differentiation
Protein Transport
Positive Regulation Of Cell Migration
Endoplasmic Reticulum Unfolded Protein Response
Cellular Response To Nutrient
Positive Regulation Of Interleukin-6 Production
Cellular Response To Insulin Stimulus
Cellular Triglyceride Homeostasis
Positive Regulation Of Vascular Wound Healing
IRE1-mediated Unfolded Protein Response
ATF6-mediated Unfolded Protein Response
Cellular Response To Glucose Starvation
Cholesterol Homeostasis
Negative Regulation Of Apoptotic Process
Positive Regulation Of MHC Class II Biosynthetic Process
Positive Regulation Of B Cell Differentiation
Positive Regulation Of T Cell Differentiation
Positive Regulation Of Fat Cell Differentiation
Positive Regulation Of Angiogenesis
Positive Regulation Of Transcription By RNA Polymerase II
Neuron Development
Fatty Acid Homeostasis
Sterol Homeostasis
Adipose Tissue Development
Cellular Response To Lipopolysaccharide
Cellular Response To Amino Acid Stimulus
Cellular Response To Fructose Stimulus
Cellular Response To Glucose Stimulus
Cellular Response To Interleukin-4
Cellular Response To Peptide Hormone Stimulus
Positive Regulation Of Plasma Cell Differentiation
Positive Regulation Of Endoplasmic Reticulum Unfolded Protein Response
Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Lactation
Response To Insulin-like Growth Factor Stimulus
Positive Regulation Of Hepatocyte Proliferation
Pathways
XBP1(S) activates chaperone genes
Drugs
Copper
Diseases
GWAS
Blood protein levels (
30072576
)
HDL cholesterol (
24097068
)
HDL cholesterol levels (
28334899
)
Refractive error (
32231278
)
Esophageal cancer (squamous cell) (
22960999
)
Esophageal squamous cell carcinoma (
25129146
)
Heel bone mineral density (
28869591
)
Mean arterial pressure (
29403010
)
Pancreatic cancer (
25086665
)
Interacting Genes
5 interacting genes:
APP
GPR37
JUN
SMAD4
XBP1
22 interacting genes:
ATF6
ATF6B
CREBZF
ESR1
FOS
FUBP3
GLI1
H1-0
H1-10
HDGF
MDM2
MTNR1B
NR0B2
PCBD2
RBL2
SRSF1
SSX4
TRIP4
UBE2I
UBE2V1
ZNF440
ZNF580
Entrez ID
3068
7494
HPRD ID
02079
01908
Ensembl ID
ENSG00000143321
ENSG00000100219
Uniprot IDs
A0A384NPW1
A8K8G0
B7Z958
P51858
A0A024R1F0
P17861
PDB IDs
1RI0
2NLU
6R5Q
6R6G
6R6P
6R7Q
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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