ANXA3 and EMG1

Data Source:
HPRD (two hybrid)

		ANXA3	EMG1
Description		annexin A3	EMG1 N1-specific pseudouridine methyltransferase
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane Axon Dendrite Phagocytic Vesicle Membrane Specific Granule Neuronal Cell Body Extracellular Exosome	Nucleus Nucleoplasm Chromosome Nucleolus Cytoplasm Small-subunit Processome
	Molecular Function	Calcium Ion Binding Calcium-dependent Phospholipid Binding Phospholipase A2 Inhibitor Activity Calcium-dependent Protein Binding	RNA Binding Protein Binding RRNA Binding Identical Protein Binding RRNA (pseudouridine) Methyltransferase Activity
	Biological Process	Phagocytosis Positive Regulation Of Endothelial Cell Migration Hippocampus Development Animal Organ Regeneration Defense Response To Bacterium Negative Regulation Of Catalytic Activity Neutrophil Degranulation Positive Regulation Of Angiogenesis Positive Regulation Of DNA Metabolic Process Positive Regulation Of DNA-binding Transcription Factor Activity Response To Glucocorticoid Response To Growth Factor	Blastocyst Development RRNA Processing Nucleologenesis Ribosomal Small Subunit Biogenesis RRNA Base Methylation
Pathways			rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs		Fluocinolone acetonide Ethanolamine Difluocortolone
Diseases			Bowen-Conradi syndrome (BCS)
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Metabolite levels ( 23823483) Non-albumin protein levels ( 22558069) Refractive error ( 32231278) Rheumatoid arthritis ( 30423114 22446963)
Interacting Genes		6 interacting genes: EMG1 IGSF21 REG3A TP53 UBR1 UNC119	15 interacting genes: ANXA3 APP CTSE FAM74A4 HIVEP1 HSD3B7 IL7R KHDRBS1 MCPH1 NAA80 PSMB7 PSME1 SLC25A38 SUMO2 ZNF768
Entrez ID		306	10436
HPRD ID		00111	12803
Ensembl ID		ENSG00000138772	ENSG00000126749
Uniprot IDs		P12429	Q92979
PDB IDs		1AII 1AXN	5FAI
Enriched GO Terms of Interacting Partners?
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