EMG1 and ANXA3

Data Source:
HPRD (two hybrid)

		EMG1	ANXA3
Description		EMG1 N1-specific pseudouridine methyltransferase	annexin A3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nucleolus Cytoplasm Small-subunit Processome	Cytoplasm Plasma Membrane Membrane Axon Dendrite Phagocytic Vesicle Membrane Specific Granule Neuronal Cell Body Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding RRNA Binding Identical Protein Binding RRNA (pseudouridine) Methyltransferase Activity	Calcium Ion Binding Calcium-dependent Phospholipid Binding Phospholipase A2 Inhibitor Activity Calcium-dependent Protein Binding
	Biological Process	Blastocyst Development RRNA Processing Nucleologenesis Ribosomal Small Subunit Biogenesis RRNA Base Methylation	Phagocytosis Positive Regulation Of Endothelial Cell Migration Hippocampus Development Animal Organ Regeneration Defense Response To Bacterium Negative Regulation Of Catalytic Activity Neutrophil Degranulation Positive Regulation Of Angiogenesis Positive Regulation Of DNA Metabolic Process Positive Regulation Of DNA-binding Transcription Factor Activity Response To Glucocorticoid Response To Growth Factor
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs			Fluocinolone acetonide Ethanolamine Difluocortolone
Diseases		Bowen-Conradi syndrome (BCS)
GWAS			Amyotrophic lateral sclerosis (sporadic) ( 24529757) Metabolite levels ( 23823483) Non-albumin protein levels ( 22558069) Refractive error ( 32231278) Rheumatoid arthritis ( 30423114 22446963)
Interacting Genes		15 interacting genes: ANXA3 APP CTSE FAM74A4 HIVEP1 HSD3B7 IL7R KHDRBS1 MCPH1 NAA80 PSMB7 PSME1 SLC25A38 SUMO2 ZNF768	6 interacting genes: EMG1 IGSF21 REG3A TP53 UBR1 UNC119
Entrez ID		10436	306
HPRD ID		12803	00111
Ensembl ID		ENSG00000126749	ENSG00000138772
Uniprot IDs		Q92979	P12429
PDB IDs		5FAI	1AII 1AXN
Enriched GO Terms of Interacting Partners?
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