H1-2 and AEBP2

Data Source:
BioGRID (pull down)

		H1-2	AEBP2
Description		H1.2 linker histone, cluster member	AE binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleosome Euchromatin Nucleus	Chromatin Nucleoplasm ESC/E(Z) Complex
	Molecular Function	Double-stranded DNA Binding RNA Binding Protein Binding Chromatin DNA Binding Nucleosomal DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Metal Ion Binding
	Biological Process	Nucleosome Assembly Nucleosome Positioning Chromosome Condensation Negative Regulation Of Chromatin Silencing Negative Regulation Of DNA Recombination	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Gene Expression, Epigenetic
Pathways		Apoptosis induced DNA fragmentation Formation of Senescence-Associated Heterochromatin Foci (SAHF)	PRC2 methylates histones and DNA PKMTs methylate histone lysines
Drugs
Diseases
GWAS			Body size at age 10 ( 32376654) Chronic mountain sickness ( 31417607) Diastolic blood pressure ( 30224653) Diverticular disease ( 30177863) Height ( 28552196) Lung function (FEV1/FVC) ( 30804560) Manganese levels ( 26025379) Obesity-related traits ( 23251661) Opioid use cessation ( 31936517) Pulmonary function ( 21946350) Response to fenofibrate (LDL cholesterol levels) ( 27002377)
Interacting Genes		30 interacting genes: AEBP2 APP ASXL1 CDC73 CSNK2A2 CTNNB1 CTR9 CUL4A DDB1 F10 IL7R IRAK4 KPNA7 KPNB1 LEO1 NASP NCL NSD1 PAF1 PARP1 POLR2A PRKCA PRKDC PUF60 RBM39 SNCA VHL WDR12 WDR5 YBX1	18 interacting genes: APP EED H1-1 H1-2 HMBOX1 JMJD6 KRTAP10-8 LDOC1 MDFI PICK1 RALYL RBBP4 SUZ12 THAP1 TRIM55 TRIM63 TSPYL2 ZNF408
Entrez ID		3006	121536
HPRD ID		07514	16477
Ensembl ID		ENSG00000187837	ENSG00000139154
Uniprot IDs		P16403	Q6ZN18
PDB IDs			5WAI 5Y0U 5Y1U 6C23 6C24
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?