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TNPO2 and NME1
Data Source:
BioGRID
(two hybrid)
TNPO2
NME1
Description
transportin 2
NME/NM23 nucleoside diphosphate kinase 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Nucleus
Cytoplasm
Mitochondrial Outer Membrane
Centrosome
Cytosol
Intermediate Filament
Membrane
Ruffle Membrane
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Molecular Function
Protein Binding
Nuclear Localization Sequence Binding
Nuclear Import Signal Receptor Activity
Magnesium Ion Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
Single-stranded DNA Binding
RNA Binding
Deoxyribonuclease Activity
Nucleoside Diphosphate Kinase Activity
Protein Binding
ATP Binding
GTP Binding
Intermediate Filament Binding
Enzyme Binding
Identical Protein Binding
Gamma-tubulin Binding
Ribosomal Small Subunit Binding
Biological Process
Protein Import Into Nucleus
Negative Regulation Of Myeloid Leukocyte Differentiation
Nucleoside Diphosphate Phosphorylation
GTP Biosynthetic Process
UTP Biosynthetic Process
CTP Biosynthetic Process
DNA Metabolic Process
Endocytosis
Lactation
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Gene Expression
Positive Regulation Of Neuron Projection Development
Response To Amine
Nucleobase-containing Small Molecule Interconversion
Hippocampus Development
Cell Differentiation
Response To Testosterone
Cellular Response To Drug
Regulation Of Apoptotic Process
Positive Regulation Of DNA Binding
Positive Regulation Of Epithelial Cell Proliferation
Response To CAMP
Cellular Response To Glucose Stimulus
Cellular Response To Fatty Acid
Pathways
Interconversion of nucleotide di- and triphosphates
Drugs
Zinc
2'-Deoxyguanosine-5'-Triphosphate
Selenocysteine
2',3'-Dehydro-2',3'-Deoxy-Thymidine 5'-Diphosphate
Adenosine Phosphonoacetic Acid
Stavudine triphosphate
Thymidine-5'- Diphosphate
2'-Deoxyguanosine-5'-Diphosphate
2',3'-dideoxy-3'-fluoro-urididine-5'-diphosphate
Guanosine-5'-Diphosphate
3'-Deoxy 3'-Amino Adenosine-5'-Diphosphate
Zidovudine diphosphate
Copper
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Diseases
GWAS
Diffuse large B-cell lymphoma or multiple sclerosis (
31407831
)
Bipolar disorder (
31043756
)
Conjunctival UV autofluorescence (CUVAF) (
25590795
)
Metabolite levels (
23823483
)
Interacting Genes
52 interacting genes:
A1CF
APIP
BEND7
BIRC7
BIRC8
BLMH
C12orf40
C1orf94
CAMK2B
CAMK2D
CAMK2G
CCDC158
CRYAB
CTAG1A
CTAG1B
ELAVL1
EXOC5
FH
FTO
FUCA2
GCH1
GSC2
KLHL2
KLHL20
KLHL3
KRT75
KRTAP8-1
NME1
NUP98
NXF1
OTX2
PACSIN3
PDLIM7
PIK3CD
PINX1
PNMA5
POU6F2
PRMT8
PYCR1
RAN
RBM45
RPL4
RPRD1B
SERTAD3
SF1
TBX2
TCL1B
TERF1
THAP6
TRIM8
ZBTB32
ZC2HC1C
31 interacting genes:
APEX1
AURKA
CCND3
FBXO24
FXR2
GORASP2
ITGB1
KSR1
LNX1
MIF
NIF3L1
NME2
NME3
NME4
NTAQ1
NUTF2
PID1
POLR1C
PRUNE1
RAC1
RORA
RORB
RRAD
SET
SMARCD1
SOX30
SREK1IP1
TERF1
TIAM1
TNPO2
TNPO3
Entrez ID
30000
4830
HPRD ID
04301
01131
Ensembl ID
ENSG00000105576
ENSG00000239672
Uniprot IDs
A0A024R7F7
O14787
Q05D48
Q4LE60
A0A384MTW7
P15531
PDB IDs
1JXV
1UCN
2HVD
2HVE
3L7U
4ENO
5UI4
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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