ACAA1 and FEM1A

Data Source:
BioGRID (two hybrid)

		ACAA1	FEM1A
Description		acetyl-CoA acyltransferase 1	fem-1 homolog A
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Peroxisome Peroxisomal Matrix Cytosol Membrane Specific Granule Lumen	Ubiquitin Ligase Complex Cytosol
	Molecular Function	Acetyl-CoA C-acetyltransferase Activity Acetyl-CoA C-acyltransferase Activity Protein Binding Acetate CoA-transferase Activity Palmitoyl-CoA Oxidase Activity Acetyl-CoA C-myristoyltransferase Activity	Protein Binding EP4 Subtype Prostaglandin E2 Receptor Binding
	Biological Process	Very Long-chain Fatty Acid Metabolic Process Protein Targeting To Peroxisome Fatty Acid Beta-oxidation Bile Acid Metabolic Process Phenylacetate Catabolic Process Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Alpha-linolenic Acid Metabolic Process Neutrophil Degranulation	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Post-translational Protein Modification Negative Regulation Of Inflammatory Response Regulation Of Ubiquitin-protein Transferase Activity
Pathways		alpha-linolenic acid (ALA) metabolism Beta-oxidation of very long chain fatty acids Neutrophil degranulation Peroxisomal protein import Peroxisomal protein import TYSND1 cleaves peroxisomal proteins	Neddylation
Drugs		Trimetazidine
Diseases
GWAS		Gut microbiota (bacterial taxa) ( 27723756)	Height ( 31562340)
Interacting Genes		4 interacting genes: FEM1A HAT1 TFCP2 TXNDC11	11 interacting genes: ACAA1 GOLGA6L9 INCA1 KIFC3 MALT1 MYOM3 NDUFAB1 OGFOD1 PPM1F PTGER4 WWOX
Entrez ID		30	55527
HPRD ID		06815	16888
Ensembl ID		ENSG00000060971	ENSG00000141965
Uniprot IDs		A0A024R2M6 A0A140VJX0 P09110	Q9BSK4
PDB IDs		2IIK
Enriched GO Terms of Interacting Partners?
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