PACSIN1 and EHBP1

Data Source:
BioGRID (two hybrid)

		PACSIN1	EHBP1
Description		protein kinase C and casein kinase substrate in neurons 1	EH domain binding protein 1
Image
GO Annotations	Cellular Component	Cytoplasm Endosome Cytosol Cytoskeleton Plasma Membrane COPI-coated Vesicle Cytoplasmic Vesicle Membrane Ruffle Membrane Axon Terminus Synapse Perinuclear Region Of Cytoplasm Photoreceptor Ribbon Synapse Presynaptic Endocytic Zone	Nucleoplasm Endosome Microtubule Organizing Center Cytosol Plasma Membrane Filamentous Actin
	Molecular Function	Protein Binding Phospholipid Binding Identical Protein Binding
	Biological Process	Cytoskeleton Organization Actin Filament Organization Regulation Of Endocytosis Negative Regulation Of Endocytosis Synaptic Vesicle Endocytosis Neuron Projection Morphogenesis Protein Localization To Membrane Protein Localization To Plasma Membrane Plasma Membrane Tubulation Positive Regulation Of Dendrite Development	Endocytosis Protein Transport Actin Cytoskeleton Organization
Pathways		Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 29273807 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Electrocardiographic traits ( 32602732) Free thyroxine concentration ( 30367059) High density lipoprotein cholesterol levels ( 30498476) Inflammatory bowel disease ( 27569725) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI ( 28552196)	Apolipoprotein B levels ( 32203549) Body mass index ( 28892062 25673413) Coffee consumption ( 31046077) Coronary artery disease ( 29212778 33020668) Crohn's disease ( 22412388) Fruit consumption ( 32066663) LDL cholesterol ( 24097068 30275531) LDL cholesterol levels ( 32203549 28334899 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Low density lipoprotein cholesterol levels ( 32154731) Prostate cancer ( 18264098 25939597 19767753) Regular attendance at a religious group ( 29970889) Total cholesterol levels ( 29403010)
Interacting Genes		25 interacting genes: ANKRD24 ARHGAP17 DNM1 EHBP1 FTH1 GAS7 HTT ITCH JADE2 KAT7 KHDRBS1 MAPT MT-ATP8 PACSIN2 PACSIN3 PLEKHF2 POT1 RTKN2 SOS1 SPTBN1 SYNJ1 TPM4 TRPV4 WASF2 WASL	3 interacting genes: EHD1 EHD2 PACSIN1
Entrez ID		29993	23301
HPRD ID		05936	10109
Ensembl ID		ENSG00000124507	ENSG00000115504
Uniprot IDs		Q5TZC3 Q9BY11	A0A140VK17 A8K930 Q8NDI1
PDB IDs		3HAH 3HAI 3Q84 3QNI	2D89 6ZSH 6ZSI 6ZSJ
Enriched GO Terms of Interacting Partners?
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