BRF1 and GTF3C4

Data Source:
HPRD (in vitro, in vivo)

		BRF1	GTF3C4
Description		BRF1 RNA polymerase III transcription initiation factor subunit	general transcription factor IIIC subunit 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Transcription Factor TFIIIB Complex Nucleus Nucleoplasm Transcription Preinitiation Complex	Transcription Factor TFIIIC Complex Nucleoplasm Mitochondrion
	Molecular Function	RNA Polymerase III General Transcription Initiation Factor Activity RNA Polymerase III Type 3 Promoter Sequence-specific DNA Binding Protein Binding TBP-class Protein Binding Metal Ion Binding	DNA Binding Histone Acetyltransferase Activity Protein Binding Enzyme Activator Activity
	Biological Process	DNA-templated Transcription, Initiation Transcription By RNA Polymerase III Transcription Initiation From RNA Polymerase III Promoter RRNA Transcription TRNA Transcription Positive Regulation Of Transcription By RNA Polymerase III Transcription Preinitiation Complex Assembly	Transcription By RNA Polymerase III Transcription Initiation From RNA Polymerase III Promoter Histone Acetylation 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III Regulation Of Catalytic Activity
Pathways		RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter	RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS		Huntington's disease progression ( 28642124) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean platelet volume ( 22139419 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet count ( 29403010 32888494 27863252) Platelet distribution width ( 27863252) Red blood cell count ( 32888494)
Interacting Genes		16 interacting genes: APP CSNK2A1 DTNBP1 GTF3C3 GTF3C4 GTF3C5 PCBD2 POLR3F RB1 RBL1 RBL2 RHOU RLIM TBP TP53 UBC	13 interacting genes: AURKA BRCA1 BRF1 GTF3C1 GTF3C2 GTF3C5 GTF3C6 H3-4 H3C15 POLR3C POLR3F SUMO2 TBP
Entrez ID		2972	9329
HPRD ID		05361	11998
Ensembl ID		ENSG00000185024	ENSG00000125484
Uniprot IDs		A0A024R6P8 Q92994 V9HVY2	B3KNH2 Q9UKN8
PDB IDs
Enriched GO Terms of Interacting Partners?
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