GTF3C4 and GTF3C2

Data Source:
HPRD (in vivo, in vitro)

		GTF3C4	GTF3C2
Description		general transcription factor IIIC subunit 4	general transcription factor IIIC subunit 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Transcription Factor TFIIIC Complex Nucleoplasm Mitochondrion	Transcription Factor TFIIIC Complex Nucleoplasm
	Molecular Function	DNA Binding Histone Acetyltransferase Activity Protein Binding Enzyme Activator Activity	DNA Binding Protein Binding
	Biological Process	Transcription By RNA Polymerase III Transcription Initiation From RNA Polymerase III Promoter Histone Acetylation 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III Regulation Of Catalytic Activity	Transcription By RNA Polymerase III 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III
Pathways		RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter	RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS			Menopause (age at onset) ( 26414677) Metabolite levels ( 23823483) Urinary albumin-to-creatinine ratio ( 32600054)
Interacting Genes		13 interacting genes: AURKA BRCA1 BRF1 GTF3C1 GTF3C2 GTF3C5 GTF3C6 H3-4 H3C15 POLR3C POLR3F SUMO2 TBP	8 interacting genes: GRIA2 GTF3A GTF3C4 PTEN RB1 SUMO2 TBP VAC14
Entrez ID		9329	2976
HPRD ID		11998	05347
Ensembl ID		ENSG00000125484	ENSG00000115207
Uniprot IDs		B3KNH2 Q9UKN8	Q8WUA4
PDB IDs
Enriched GO Terms of Interacting Partners?
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