GSR and C11orf49

Data Source:
BioGRID (two hybrid)

		GSR	C11orf49
Description		glutathione-disulfide reductase	chromosome 11 open reading frame 49
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Cytosol External Side Of Plasma Membrane Extracellular Exosome
	Molecular Function	Glutathione-disulfide Reductase Activity Electron Transfer Activity Flavin Adenine Dinucleotide Binding NADP Binding	Protein Binding
	Biological Process	Glutathione Metabolic Process Nucleobase-containing Small Molecule Interconversion Electron Transport Chain Cellular Response To Oxidative Stress Cell Redox Homeostasis Cellular Oxidant Detoxification
Pathways
Drugs		Glutathione NADH Carmustine 3,6-dihydroxy-xanthene-9-propionic acid 3-sulfino-L-alanine Glutathionylspermidine disulfide 3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol Flavin adenine dinucleotide Glutathione disulfide 3-nitro-L-tyrosine 2-(2-PHENYL-3-PYRIDIN-2-YL-4,5,6,7-TETRAHYDRO-2H-ISOPHOSPHINDOL-1-YL)PYRIDINE 6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)HEXANOIC ACID Cannabidiol Copper Medical Cannabis Nabiximols
Diseases
GWAS			Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) D-dimer levels ( 21502573) HDL cholesterol levels ( 32203549) Intraocular pressure ( 29617998) Neurociticism ( 29500382)
Interacting Genes		4 interacting genes: C11orf49 CDC42 OCM2 PJA1	19 interacting genes: ARHGEF15 CDC16 ENY2 FH GCA GSR PHF1 PNMA5 PRKAR1A PSMA1 RAB17 RAB29 RBM48 RPL8 RPS3A TXN2 UBE3A UBQLN4 ZFHX3
Entrez ID		2936	79096
HPRD ID		00704	08332
Ensembl ID		ENSG00000104687	ENSG00000149179
Uniprot IDs		P00390 V9HW90	B4DUV7 Q9H6J7
PDB IDs		1ALG 1BWC 1DNC 1GRA 1GRB 1GRE 1GRF 1GRG 1GRH 1GRT 1GSN 1K4Q 1XAN 2AAQ 2GH5 2GRT 3DJG 3DJJ 3DK4 3DK8 3DK9 3GRS 3GRT 3SQP 4GR1 4GRT 5GRT
Enriched GO Terms of Interacting Partners?
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