SAP30BP and RPS6KA6

Data Source:
BioGRID (two hybrid)

		SAP30BP	RPS6KA6
Description		SAP30 binding protein	ribosomal protein S6 kinase A6
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Intermediate Filament Cytoskeleton	Fibrillar Center Nucleoplasm Nucleolus Cytoplasm Mitochondrion Cytosol
	Molecular Function	Protein Binding	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Ribosomal Protein S6 Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Regulation Of Transcription, DNA-templated Apoptotic Process Positive Regulation Of Cell Death	DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Signal Transduction Central Nervous System Development Peptidyl-serine Phosphorylation Negative Regulation Of Embryonic Development Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Mesoderm Development
Pathways		NoRC negatively regulates rRNA expression	Recycling pathway of L1 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling RSK activation RSK activation
Drugs			Fostamatinib
Diseases
GWAS		Rotator cuff tears ( 26350878)
Interacting Genes		26 interacting genes: CCNL1 CSNK2A1 DHX8 FHL2 FHL3 FRA10AC1 GOLGA2 GSK3B MLX OGT PRKAR1B PUF60 RBM17 RBM39 RPS6KA6 SAP30 SNCA SUPT5H TFIP11 THAP1 THOC1 U2AF2 WDR77 WDR83 ZNF212 ZNF408	28 interacting genes: ADIRF APP CEBPZ CENPB CLEC3B DHX34 DNAJC13 DNMT1 ERG28 FBN3 FZD5 LMO4 MASP1 MED24 MICAL1 MPP1 NR4A1 RBPJ RPLP1 RXRA SAP30BP SPRED2 SPTBN4 SYNE4 UBE2I UFM1 ZNF227 ZNF746
Entrez ID		29115	27330
HPRD ID		17094	02250
Ensembl ID		ENSG00000161526	ENSG00000072133
Uniprot IDs		A0A024R8R0 Q9UHR5	Q9UK32
PDB IDs			6G76 6G77 6G78
Enriched GO Terms of Interacting Partners?
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