GPR42 and PLPP1

Data Source:
BioGRID (two hybrid)

		GPR42	PLPP1
Description		G protein-coupled receptor 42	phospholipid phosphatase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane Caveola Membrane Apical Plasma Membrane Membrane Raft Extracellular Exosome
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding	Diacylglycerol Diphosphate Phosphatase Activity Protein Binding Phosphatidate Phosphatase Activity Sphingosine-1-phosphate Phosphatase Activity Lipid Phosphatase Activity Ceramide-1-phosphate Phosphatase Activity
	Biological Process	G Protein-coupled Receptor Signaling Pathway	Phospholipid Metabolic Process Sphingosine Metabolic Process Ceramide Metabolic Process Signal Transduction Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Cell Population Proliferation Regulation Of Lipid Metabolic Process Sphingolipid Biosynthetic Process Intracellular Steroid Hormone Receptor Signaling Pathway Androgen Receptor Signaling Pathway Phospholipid Dephosphorylation
Pathways			Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS			Cocaine dependence ( 31212010) Heel bone mineral density ( 30598549 28869591)
Interacting Genes		104 interacting genes: ADIPOQ ALOX5AP ANKRD46 APOD ATP13A1 ATP4B ATP6V0B ATP6V0C BNIP3 BTN2A2 C1GALT1 CCDC167 CCL4L2 CD300C CD79A CLCA4 CLEC2D COMT CTXN3 CXCL16 CXCL9 DRAM1 EFNA5 EMP1 ERMP1 FAM3C FXYD3 FXYD6 GJB2 GOSR2 GPR37L1 GYPC IER3IP1 IGFBP5 IL1RL1 ITGAM JPH1 KCNA1 KLRG1 LAT LEPROTL1 LHFPL5 LNPEP LTC4S MFSD5 MFSD6 MGAM MS4A1 NDUFB11 NINJ2 NRM NSG1 PAEP PLP1 PLPP1 PMP22 PNLIPRP1 RPRM RTP2 RUSF1 SCD SERINC1 SERP2 SERTM1 SLC30A2 SLC30A3 SLC30A8 SLC35E4 SLC38A1 SLC38A7 SLC39A2 SLC41A1 SLC41A2 SMCO4 SMIM3 STATH STRIT1 STX8 SYNDIG1 SYNGR1 TEX264 TF TM4SF4 TMBIM6 TMEM140 TMEM147 TMEM182 TMEM19 TMEM237 TMEM239 TMEM242 TMEM262 TMEM30B TMEM60 TMEM65 TRARG1 TREX1 TSPO2 YIF1A YIPF1 YIPF2 YIPF4 YIPF6 ZFPL1	5 interacting genes: CREB3 FAHD1 FXYD1 GPR42 SSMEM1
Entrez ID		2866	8611
HPRD ID		16033	06178
Ensembl ID		ENSG00000126251	ENSG00000067113
Uniprot IDs		A0A0K0PUY3 O15529	A0A024QZS3 A0A024QZU7 O14494
PDB IDs
Enriched GO Terms of Interacting Partners?
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