SERGEF and DPH3

		SERGEF	DPH3
Description		secretion regulating guanine nucleotide exchange factor	diphthamide biosynthesis 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding Metal Ion Binding
	Biological Process	Signal Transduction Negative Regulation Of Protein Secretion Regulation Of Catalytic Activity	TRNA Wobble Uridine Modification Peptidyl-diphthamide Biosynthetic Process From Peptidyl-histidine Negative Regulation Of Protein Secretion Positive Regulation Of Binding
Pathways			Synthesis of diphthamide-EEF2
Drugs
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30643258) Body mass index ( 26426971)
Interacting Genes		8 interacting genes: DPH3 EXOC2 FOXH1 HGS KDM1A PITX1 PRMT6 SPAG8	6 interacting genes: ADIPOR1 MEOX2 PIH1D2 RPL8 SERGEF ZNF438
Entrez ID		26297	285381
HPRD ID		06926	16412
Ensembl ID		ENSG00000129158	ENSG00000154813
Uniprot IDs		A8K8C1 Q9UGK8	Q96FX2
PDB IDs			2JR7
Enriched GO Terms of Interacting Partners?
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