TPRX1 and NELFB

Data Source:
BioGRID (two hybrid)

		TPRX1	NELFB
Description		tetrapeptide repeat homeobox 1	negative elongation factor complex member B
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleoplasm Cytoplasm NELF Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific	RNA Binding Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Cell Population Proliferation Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Stem Cell Differentiation Positive Regulation Of Viral Transcription Negative Regulation Of Stem Cell Differentiation
Pathways			Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation NTRK3 as a dependence receptor
Drugs
Diseases
GWAS
Interacting Genes		18 interacting genes: ATXN1 FANCG GOLGA2 GOLGA6L9 INCA1 KRTAP19-7 KRTAP6-2 MKRN3 NELFB OIP5 PRR20A PRR20B PRR20C PRR20D PRR20E SERTAD3 USHBP1 ZNRF4	16 interacting genes: BRCA1 CEBPE DENR ESR1 FOS HSPA9 JUN KHDRBS3 MAPK6 MGST1 NELFA NELFCD NELFE NTRK3 RAD51 TPRX1
Entrez ID		284355	25920
HPRD ID		13447	10845
Ensembl ID		ENSG00000178928	ENSG00000188986
Uniprot IDs		Q8N7U7	Q8WX92
PDB IDs			6GML
Enriched GO Terms of Interacting Partners?
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