LAMA1 and NT5E

Data Source:
HPRD (in vivo)

		LAMA1	NT5E
Description		laminin subunit alpha 1	5'-nucleotidase ecto
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Laminin-1 Complex Laminin-3 Complex Extracellular Space Cell-cell Junction Membrane Extracellular Matrix Collagen-containing Extracellular Matrix	Nucleoplasm Cytosol Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Anchored Component Of Membrane Extracellular Exosome
	Molecular Function	Signaling Receptor Binding Extracellular Matrix Structural Constituent Protein Binding Protein C-terminus Binding Glycosphingolipid Binding	Nucleotide Binding Protein Binding 5'-nucleotidase Activity Metal Ion Binding
	Biological Process	Morphogenesis Of An Epithelial Sheet Protein Phosphorylation Cell Adhesion Cell Surface Receptor Signaling Pathway Axon Guidance Animal Organ Morphogenesis Tissue Development Regulation Of Cell Adhesion Extracellular Matrix Organization Regulation Of Cell Migration Camera-type Eye Development Establishment Of Epithelial Cell Apical/basal Polarity Regulation Of Embryonic Development Blood Vessel Morphogenesis Epithelial Tube Branching Involved In Lung Morphogenesis Branching Involved In Salivary Gland Morphogenesis Retinal Blood Vessel Morphogenesis	Purine Nucleotide Catabolic Process AMP Catabolic Process DNA Metabolic Process Leukocyte Cell-cell Adhesion Dephosphorylation NAD Metabolic Process Adenosine Biosynthetic Process Pyrimidine Nucleoside Catabolic Process Negative Regulation Of Inflammatory Response
Pathways		Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans L1CAM interactions MET activates PTK2 signaling	Nicotinate metabolism Pyrimidine catabolism Purine catabolism Purinergic signaling in leishmaniasis infection
Drugs		Lanoteplase	Pentoxifylline
Diseases			Calcification of joints and arteries
GWAS		Adverse response to drug ( 30420678) Response to citalopram treatment ( 22760553) Type 2 diabetes ( 30054458 22693455 30297969 32499647)	Blood metabolite levels ( 24816252) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Lung function ( 31902109) Metabolic traits ( 21886157)
Interacting Genes		20 interacting genes: ACHE APCS APP C3 COL7A1 DAG1 FBLN2 HSPG2 ITGA1 ITGA2 ITGB1 MEP1A NID1 NT5E PLAT PLG SAA1 SAA2 TMPRSS6 UBC	6 interacting genes: ACTB AFF1 FN1 LAMA1 RNF24 ZNRF4
Entrez ID		284217	4907
HPRD ID		01033	00552
Ensembl ID		ENSG00000101680	ENSG00000135318
Uniprot IDs		P25391	P21589 Q6NZX3
PDB IDs			4H1S 4H1Y 4H2B 4H2F 4H2G 4H2I 6HXW 6S7F 6S7H 6TVE 6TVG 6TVX 6TW0 6TWA 6TWF 6XUE 6XUG 6XUQ 6Z9B 6Z9D 7JV8 7JV9
Enriched GO Terms of Interacting Partners?
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