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NT5E

Description 5'-nucleotidase ecto
Image
GO Annotations Cellular Component
  • Nucleoplasm
  • Cytosol
  • Plasma Membrane
  • External Side Of Plasma Membrane
  • Cell Surface
  • Membrane
  • Anchored Component Of Membrane
  • Extracellular Exosome
Molecular Function
  • Nucleotide Binding
  • Protein Binding
  • 5'-nucleotidase Activity
  • Metal Ion Binding
Biological Process
  • Purine Nucleotide Catabolic Process
  • AMP Catabolic Process
  • DNA Metabolic Process
  • Leukocyte Cell-cell Adhesion
  • Dephosphorylation
  • NAD Metabolic Process
  • Adenosine Biosynthetic Process
  • Pyrimidine Nucleoside Catabolic Process
  • Negative Regulation Of Inflammatory Response
Pathways
  • Nicotinate metabolism
  • Pyrimidine catabolism
  • Purine catabolism
  • Purinergic signaling in leishmaniasis infection
Drugs
  • Pentoxifylline
Diseases
  • Calcification of joints and arteries
GWAS
  • Blood metabolite levels ( 24816252)
  • Hippocampal volume in Alzheimer's disease dementia ( 29274321)
  • Lung function ( 31902109)
  • Metabolic traits ( 21886157)
Novel Interacting Genes 1 novel interacting genes: ATP6AP1
Interacting Genes 6 interacting genes: ACTB AFF1 FN1 LAMA1 RNF24 ZNRF4
Entrez ID 4907
HPRD ID 00552
Ensembl ID ENSG00000135318
Uniprot IDs P21589 Q6NZX3
PDB IDs 4H1S 4H1Y 4H2B 4H2F 4H2G 4H2I 6HXW 6S7F 6S7H 6TVE 6TVG 6TVX 6TW0 6TWA 6TWF 6XUE 6XUG 6XUQ 6Z9B 6Z9D 7JV8 7JV9
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025