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PGP and RNF2
Data Source:
BioGRID
(two hybrid, affinity chromatography technology)
PGP
RNF2
Description
phosphoglycolate phosphatase
ring finger protein 2
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Ubiquitin Ligase Complex
Euchromatin
Sex Chromatin
Nucleus
Nucleoplasm
Nuclear Body
PcG Protein Complex
PRC1 Complex
MLL1 Complex
Molecular Function
Glycerol-1-phosphatase Activity
Magnesium Ion Binding
Protein Tyrosine Phosphatase Activity
Phosphoglycolate Phosphatase Activity
Phosphatase Activity
Glycerol-3-phosphatase Activity
Nucleotide Phosphatase Activity, Acting On Free Nucleotides
Chromatin Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Activity
RING-like Zinc Finger Domain Binding
Biological Process
Glycerol Biosynthetic Process
Glycerophospholipid Metabolic Process
Dephosphorylation
Peptidyl-tyrosine Dephosphorylation
Negative Regulation Of Gluconeogenesis
Negative Regulation Of Transcription By RNA Polymerase II
Mitotic Cell Cycle
Gastrulation With Mouth Forming Second
Germ Cell Development
Anterior/posterior Axis Specification
Gene Expression
Histone H2A Monoubiquitination
Histone H2A-K119 Monoubiquitination
Negative Regulation Of DNA-binding Transcription Factor Activity
Negative Regulation Of G0 To G1 Transition
Pathways
Glycolysis
Oxidative Stress Induced Senescence
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription cofactors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA methylation proteins
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS
Height (
28552196
31562340
)
Weight (
28552196
)
Clopidogrel active metabolite levels (
28207573
)
Itch intensity from mosquito bite adjusted by bite size (
28199695
)
Obesity-related traits (
23251661
)
Interacting Genes
2 interacting genes:
LIG4
RNF2
59 interacting genes:
ABCB1
AMBRA1
AUTS2
BAALC
BMI1
CASP3
CASP9
CBX2
CBX4
DYSF
ERG
H2AC18
H2AC20
H2AC4
H3-4
KAT8
KMT2A
MBD1
MTNR1A
OTUD6A
PCGF1
PCGF2
PCGF3
PCGF6
PGP
PHB2
PHC1
PHC2
PLK1
PSMC4
RING1
RRM1
RYBP
SIK1
SMURF2
SSX2
TARDBP
TFCP2
TSC22D2
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2J1
UBE2K
UBE2L3
UBE2U
UBE2V1
UBE2V2
UBE2W
USP11
USP19
WASHC1
YAF2
Entrez ID
283871
6045
HPRD ID
19077
07028
Ensembl ID
ENSG00000184207
ENSG00000121481
Uniprot IDs
A6NDG6
Q99496
PDB IDs
2H0D
3GS2
3H8H
3IXS
3RPG
4R8P
4S3O
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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