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GNG3 and GNB3
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(two hybrid)
GNG3
GNB3
Description
G protein subunit gamma 3
G protein subunit beta 3
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Heterotrimeric G-protein Complex
Plasma Membrane
Postsynaptic Density
Dendrite
G-protein Beta/gamma-subunit Complex
Cell Body
Cytoplasm
Cytosol
Heterotrimeric G-protein Complex
Plasma Membrane
Dendrite
Cell Body
Extracellular Exosome
Molecular Function
GTPase Activity
Protein Binding
G-protein Beta-subunit Binding
GTPase Activity
Protein Binding
Spectrin Binding
G-protein Gamma-subunit Binding
GTPase Binding
Biological Process
Activation Of MAPK Activity
G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Protein Folding
Cell Volume Homeostasis
G Protein-coupled Receptor Signaling Pathway
Regulation Of Blood Pressure
Regulation Of Gene Expression
Regulation Of Glucose Metabolic Process
Regulation Of Hormone Metabolic Process
Regulation Of Fat Cell Differentiation
Regulation Of Feeding Behavior
Regulation Of Cholesterol Metabolic Process
Regulation Of Triglyceride Metabolic Process
Regulation Of Locomotion Involved In Locomotory Behavior
Regulation Of Phospholipid Metabolic Process
Pathways
Activation of G protein gated Potassium channels
Glucagon signaling in metabolic regulation
G-protein activation
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
ADP signalling through P2Y purinoceptor 12
G beta:gamma signalling through PI3Kgamma
Prostacyclin signalling through prostacyclin receptor
Prostacyclin signalling through prostacyclin receptor
Adrenaline,noradrenaline inhibits insulin secretion
Adrenaline,noradrenaline inhibits insulin secretion
Ca2+ pathway
Ca2+ pathway
G alpha (q) signalling events
G alpha (12/13) signalling events
G beta:gamma signalling through PLC beta
G alpha (s) signalling events
ADP signalling through P2Y purinoceptor 1
ADP signalling through P2Y purinoceptor 1
G alpha (i) signalling events
G alpha (z) signalling events
Glucagon-type ligand receptors
Thromboxane signalling through TP receptor
Vasopressin regulates renal water homeostasis via Aquaporins
Thrombin signalling through proteinase activated receptors (PARs)
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
G beta:gamma signalling through BTK
G beta:gamma signalling through CDC42
Extra-nuclear estrogen signaling
ADORA2B mediated anti-inflammatory cytokines production
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Activation of G protein gated Potassium channels
Glucagon signaling in metabolic regulation
G-protein activation
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
ADP signalling through P2Y purinoceptor 12
G beta:gamma signalling through PI3Kgamma
Prostacyclin signalling through prostacyclin receptor
Prostacyclin signalling through prostacyclin receptor
Adrenaline,noradrenaline inhibits insulin secretion
Adrenaline,noradrenaline inhibits insulin secretion
Ca2+ pathway
Ca2+ pathway
G alpha (q) signalling events
G alpha (12/13) signalling events
G beta:gamma signalling through PLC beta
G alpha (s) signalling events
ADP signalling through P2Y purinoceptor 1
ADP signalling through P2Y purinoceptor 1
G alpha (i) signalling events
G alpha (z) signalling events
Glucagon-type ligand receptors
Thromboxane signalling through TP receptor
Vasopressin regulates renal water homeostasis via Aquaporins
Thrombin signalling through proteinase activated receptors (PARs)
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
G beta:gamma signalling through BTK
G beta:gamma signalling through CDC42
Extra-nuclear estrogen signaling
ADORA2B mediated anti-inflammatory cytokines production
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs
Diseases
GWAS
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Central retinal vein equivalent (
26567291
)
High myopia (
31816047
)
Macular thickness (
30535121
)
Myopia (
27182965
)
Refractive error (
32231278
)
Response to Vitamin E supplementation (
22437554
)
Spherical equivalent or myopia (age of diagnosis) (
29808027
)
Interacting Genes
8 interacting genes:
GNB1
GNB2
GNB3
GNB4
GNB5
NTAQ1
SS18L2
TRIM73
13 interacting genes:
CIDEB
GNG10
GNG12
GNG13
GNG2
GNG3
GNG4
GNG5
GNG7
GNG8
GRK2
RASD2
TGFBR1
Entrez ID
2785
2784
HPRD ID
12337
00743
Ensembl ID
ENSG00000162188
ENSG00000111664
Uniprot IDs
P63215
E9PCP0
F1T0G5
P16520
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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