GNG3 and SS18L2

Data Source:
BioGRID (two hybrid)

		GNG3	SS18L2
Description		G protein subunit gamma 3	SS18 like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Heterotrimeric G-protein Complex Plasma Membrane Postsynaptic Density Dendrite G-protein Beta/gamma-subunit Complex Cell Body	Nucleus
	Molecular Function	GTPase Activity Protein Binding G-protein Beta-subunit Binding	Transcription Coactivator Activity Protein Binding
	Biological Process	Activation Of MAPK Activity G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration	Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Dendrite Morphogenesis
Pathways		Activation of G protein gated Potassium channels Glucagon signaling in metabolic regulation G-protein activation Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Glucagon-like Peptide-1 (GLP1) regulates insulin secretion ADP signalling through P2Y purinoceptor 12 G beta:gamma signalling through PI3Kgamma Prostacyclin signalling through prostacyclin receptor Prostacyclin signalling through prostacyclin receptor Adrenaline,noradrenaline inhibits insulin secretion Adrenaline,noradrenaline inhibits insulin secretion Ca2+ pathway Ca2+ pathway G alpha (q) signalling events G alpha (12/13) signalling events G beta:gamma signalling through PLC beta G alpha (s) signalling events ADP signalling through P2Y purinoceptor 1 ADP signalling through P2Y purinoceptor 1 G alpha (i) signalling events G alpha (z) signalling events Glucagon-type ligand receptors Thromboxane signalling through TP receptor Vasopressin regulates renal water homeostasis via Aquaporins Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs) Presynaptic function of Kainate receptors Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding G beta:gamma signalling through BTK G beta:gamma signalling through CDC42 Extra-nuclear estrogen signaling ADORA2B mediated anti-inflammatory cytokines production Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		8 interacting genes: GNB1 GNB2 GNB3 GNB4 GNB5 NTAQ1 SS18L2 TRIM73	7 interacting genes: EMC2 FBXO7 GNG3 LYPD6 MBD5 TMEM17 YY1AP1
Entrez ID		2785	51188
HPRD ID		12337	09399
Ensembl ID		ENSG00000162188	ENSG00000008324
Uniprot IDs		P63215	A0A024R2Q8 Q9UHA2
PDB IDs
Enriched GO Terms of Interacting Partners?
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