CENPB and RPS6KA6

Data Source:
BioGRID (two hybrid)

		CENPB	RPS6KA6
Description		centromere protein B	ribosomal protein S6 kinase A6
Image
GO Annotations	Cellular Component	Chromosome, Centromeric Region Condensed Chromosome, Centromeric Region Nucleus Nucleoplasm Chromosome Pericentric Heterochromatin Nuclear Body	Fibrillar Center Nucleoplasm Nucleolus Cytoplasm Mitochondrion Cytosol
	Molecular Function	DNA Binding Chromatin Binding Satellite DNA Binding Centromeric DNA Binding Sequence-specific DNA Binding	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Ribosomal Protein S6 Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process		DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Signal Transduction Central Nervous System Development Peptidyl-serine Phosphorylation Negative Regulation Of Embryonic Development Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Mesoderm Development
Pathways			Recycling pathway of L1 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling RSK activation RSK activation
Drugs			Fostamatinib
Diseases
GWAS
Interacting Genes		20 interacting genes: ADRB2 ANXA7 APP CDKN1A CENPW CSNK2B FBXO25 GADD45A GFI1B GSK3B HAND2 NR3C1 PARP1 PARP2 PIN1 RPS6KA6 SH2D3A SMN1 TAC1 TK1	28 interacting genes: ADIRF APP CEBPZ CENPB CLEC3B DHX34 DNAJC13 DNMT1 ERG28 FBN3 FZD5 LMO4 MASP1 MED24 MICAL1 MPP1 NR4A1 RBPJ RPLP1 RXRA SAP30BP SPRED2 SPTBN4 SYNE4 UBE2I UFM1 ZNF227 ZNF746
Entrez ID		1059	27330
HPRD ID		00314	02250
Ensembl ID		ENSG00000125817	ENSG00000072133
Uniprot IDs		P07199	Q9UK32
PDB IDs		1BW6 1HLV 1UFI 6KDR	6G76 6G77 6G78
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?