KLHL20 and DUSP21

Data Source:
BioGRID (two hybrid)

		KLHL20	DUSP21
Description		kelch like family member 20	dual specificity phosphatase 21
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Actin Cytoskeleton PML Body Axon Dendrite Cul3-RING Ubiquitin Ligase Complex Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Mitochondrial Matrix Extrinsic Component Of Mitochondrial Inner Membrane
	Molecular Function	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding Interferon-gamma Binding	Protein Tyrosine Phosphatase Activity Protein Binding MAP Kinase Tyrosine/serine/threonine Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Golgi To Endosome Transport Cytoskeleton Organization Protein Transport Protein Ubiquitination Response To Interferon-alpha Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Protein K33-linked Ubiquitination	Inactivation Of MAPK Activity Peptidyl-tyrosine Dephosphorylation
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Feeling miserable ( 29500382)
Interacting Genes		41 interacting genes: ACTA1 ARHGEF12 ATG9A BCL6 BEX1 BEX2 C1orf216 C20orf85 C21orf58 CEP126 CIDEC CLCNKA COL8A1 CORO7 CRK CRMP1 DUSP21 ECT2 ENKD1 EPAS1 ERG28 GBP2 HR IVNS1ABP KLHL38 LRIF1 LUC7L2 MTNR1A NEDD9 NTAQ1 PIN1 PML PRMT6 RANBP3 RECK SLC13A5 STK16 SUV39H1 TFAP2D TNPO2 USP20	33 interacting genes: APP ATP23 BPIFA1 CPNE7 CTBP2 EPHA3 EPHA5 ERBB3 ERBB4 EYA2 FAAP20 GET4 GORASP2 IGF1R KLHL20 KRT33B KRTAP11-1 MAP2K5 MYO15B OIP5 POU4F3 PTK7 RFX6 RGS2 ROR1 ROR2 SUOX TEX11 TOX3 TRAF1 UBQLN2 USP2 ZMAT1
Entrez ID		27252	63904
HPRD ID		13918	06494
Ensembl ID		ENSG00000076321	ENSG00000189037
Uniprot IDs		Q9Y2M5	Q9H596
PDB IDs		5YQ4 6GY5
Enriched GO Terms of Interacting Partners?
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