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PDCD4 and LRRK1
Data Source:
BioGRID
(pull down)
PDCD4
LRRK1
Description
programmed cell death 4
leucine rich repeat kinase 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Cytoplasm
Mitochondrion
Cytosol
Intracellular Membrane-bounded Organelle
Molecular Function
RNA Binding
Protein Binding
Protein Serine/threonine Phosphatase Activity
Protein Binding
ATP Binding
GTP Binding
Identical Protein Binding
Metal Ion Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Biological Process
Apoptotic Process
Cell Aging
BMP Signaling Pathway
Interleukin-12-mediated Signaling Pathway
Negative Regulation Of Apoptotic Process
Negative Regulation Of JUN Kinase Activity
Negative Regulation Of Cell Cycle
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Inflammatory Response
Epithelial To Mesenchymal Transition Involved In Cardiac Fibroblast Development
Cellular Response To Lipopolysaccharide
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of NIK/NF-kappaB Signaling
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Myofibroblast Differentiation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation
Positive Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process
Positive Regulation Of Endothelial Cell Apoptotic Process
Protein Phosphorylation
Protein Dephosphorylation
Signal Transduction
Osteoclast Development
Bone Resorption
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Negative Regulation Of Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Intracellular Signal Transduction
Pathways
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS
Fish- and plant-related diet (
32066663
)
Central corneal thickness (
32528159
28171582
31798171
29760442
)
Corneal structure (
23291589
)
Height (
28552196
)
Interacting Genes
16 interacting genes:
APOE
BTRC
CSNK2A1
EIF4A2
EIF4A3
EIF4G1
IBTK
LRRK1
PSEN1
PSEN2
RPL5
RPLP1
RPS13
RPS6KA1
SKP2
SUMO2
51 interacting genes:
ABL1
BAG1
BAG2
BAG3
BAG5
BLOC1S5
C11orf52
CBLB
CCL21
CD2BP2
CDC42EP3
CHGB
CKAP2
CLVS1
CPLX3
CWC15
ECHS1
EGFR
ENKUR
EPHA8
FAM184A
FBXL14
FGFR2
FLT4
FOXP1
GAK
GNAZ
GPBP1L1
ITCH
KIF20A
MATK
MTG1
NEK1
NUDT16L1
ODF2
PAK6
PDCD4
PLK1
POLR2M
RAB29
RET
SCEL
SH2D2A
SNX21
SNX9
STUB1
TCF25
TEC
TEX33
TIRAP
VGLL4
Entrez ID
27250
79705
HPRD ID
10549
14319
Ensembl ID
ENSG00000150593
ENSG00000154237
Uniprot IDs
B4DKX4
Q53EL6
Q38SD2
PDB IDs
2GGF
2KZT
2RG8
2ZU6
3EIJ
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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