ARHGEF16 and HNRNPH1

Data Source:
BioGRID (two hybrid)

		ARHGEF16	HNRNPH1
Description		Rho guanine nucleotide exchange factor 16	heterogeneous nuclear ribonucleoprotein H1
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GO Annotations	Cellular Component	Cytosol	Nucleus Nucleoplasm Cytosol Membrane Catalytic Step 2 Spliceosome Ribonucleoprotein Complex
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding PDZ Domain Binding Receptor Tyrosine Kinase Binding Small GTPase Binding Cadherin Binding	RNA Binding Protein Binding Poly(U) RNA Binding Identical Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Apoptotic Process Regulation Of Small GTPase Mediated Signal Transduction Cell Chemotaxis Activation Of GTPase Activity Positive Regulation Of Protein Localization To Plasma Membrane	MRNA Splicing, Via Spliceosome RNA Processing Fibroblast Growth Factor Receptor Signaling Pathway RNA Metabolic Process Regulation Of RNA Splicing
Pathways		NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events	FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs			Copper
Diseases
GWAS		Dental caries (decayed, missing and filled tooth surfaces) ( 31533690) Response to statin therapy ( 20339536)	Daytime sleep phenotypes ( 27126917) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		9 interacting genes: CKAP5 HNRNPH1 LASP1 LMNA LNX1 MAGED1 MAPK1IP1L TFG YWHAQ	132 interacting genes: APBB1 ARHGEF16 CATSPER1 CCDC120 CCNK CRMP1 DDX17 DDX5 DUX4 DZIP3 ENKD1 ERG GPANK1 GPS2 HIPK3 HNRNPF HNRNPH3 HNRNPM KHSRP KRTAP13-2 LMO1 LMO3 LNX1 MAGED1 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MRPL53 MSI2 MTNR1A MYPOP NCBP1 NCBP2 NDRG1 NFKBID NUDT16L1 OXER1 PATZ1 PCAT1 PEX5 PIN1 POLR1C PPP1R32 RALY RAMAC RBFOX2 RBM38 RNF4 SF1 SF3B4 SNRPB SNRPC SPG21 SREK1 SUMO2 SUMO4 TCERG1 TEKT3 TEKT4 TOM1L1 YPEL3 YWHAG YWHAQ
Entrez ID		27237	3187
HPRD ID		12478	03021
Ensembl ID		ENSG00000130762	ENSG00000169045
Uniprot IDs		B3KTS4 Q5VV41	A0A384MEJ3 P31943
PDB IDs		1X6B	2LXU 6DHS
Enriched GO Terms of Interacting Partners?
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