ARHGEF16 and TFG

Data Source:
BioGRID (two hybrid)

		ARHGEF16	TFG
Description		Rho guanine nucleotide exchange factor 16	trafficking from ER to golgi regulator
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Golgi Membrane Cytoplasm Cytosol Intracellular Membrane-bounded Organelle Endoplasmic Reticulum Exit Site
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding PDZ Domain Binding Receptor Tyrosine Kinase Binding Small GTPase Binding Cadherin Binding	Protein Binding Identical Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Apoptotic Process Regulation Of Small GTPase Mediated Signal Transduction Cell Chemotaxis Activation Of GTPase Activity Positive Regulation Of Protein Localization To Plasma Membrane	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling COPII Vesicle Coating
Pathways		NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events	COPII-mediated vesicle transport
Drugs
Diseases			Non-small cell lung cancer Thyroid cancer
GWAS		Dental caries (decayed, missing and filled tooth surfaces) ( 31533690) Response to statin therapy ( 20339536)	Refractive error ( 32231278)
Interacting Genes		9 interacting genes: CKAP5 HNRNPH1 LASP1 LMNA LNX1 MAGED1 MAPK1IP1L TFG YWHAQ	73 interacting genes: ANXA11 ARHGEF16 ARL15 BOLL BPIFA1 C19orf54 CEP126 CEP55 CRMP1 CRX CSTF2 DAZAP2 DVL3 ERG28 EWSR1 EYA2 FAM168A FOXH1 GBP2 GPRASP1 GRB2 HGS HNRNPF INCA1 INTS11 KHDC1 KRTAP26-1 LASP1 LENG8 MAGED1 MAPK1IP1L MED21 MED25 METTL27 MSS51 MYOT NADSYN1 NID2 OXER1 PEF1 PFDN5 PIN1 PLA2G10 PLEKHG4 PLSCR1 POU2AF1 PPP1R32 PRR20A PRR20B PRR20C PRR20D PRR20E PTPN6 RBPMS RIPPLY2 RNF4 SEC24A SF3A2 SF3B4 SMUG1 SPG21 STAT5B STH TBX19 TEX37 TRIM25 TSSK2 UBAP2 UBE2I VPS37C WWOX ZMYM5 ZNF34
Entrez ID		27237	10342
HPRD ID		12478	03932
Ensembl ID		ENSG00000130762	ENSG00000114354
Uniprot IDs		B3KTS4 Q5VV41	Q05BK6 Q92734
PDB IDs		1X6B
Enriched GO Terms of Interacting Partners?
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