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GNMT and GAGE2A
Data Source:
BioGRID
(two hybrid)
GNMT
GAGE2A
Description
glycine N-methyltransferase
G antigen 2A
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Cellular_component
Molecular Function
Protein Binding
Folic Acid Binding
Glycine Binding
Glycine N-methyltransferase Activity
Identical Protein Binding
S-adenosyl-L-methionine Binding
Molecular_function
Protein Binding
Biological Process
Glycogen Metabolic Process
Regulation Of Gluconeogenesis
Cellular Protein Modification Process
Methionine Metabolic Process
One-carbon Metabolic Process
Methylation
Cellular Nitrogen Compound Metabolic Process
S-adenosylhomocysteine Metabolic Process
S-adenosylmethionine Metabolic Process
Protein Homotetramerization
Sarcosine Metabolic Process
Biological_process
Pathways
Metabolism of ingested SeMet, Sec, MeSec into H2Se
Glyoxylate metabolism and glycine degradation
Drugs
Ademetionine
Glycine
S-adenosyl-L-homocysteine
Diseases
Hypermethioninemia; Methionine adenosyltransferase deficiency; S-adenosylhomocysteine hydrolase deficiency
GWAS
Apolipoprotein B levels (
32203549
)
Blood protein levels (
30072576
29875488
)
LDL cholesterol levels (
32203549
)
Plasma homocysteine levels (post-methionine load test) (
24651765
)
Interacting Genes
30 interacting genes:
ADAMTSL4
ARR3
ARRB1
CCDC153
COX7B
CTNS
FRG1
GABRQ
GAGE2A
HDAC7
HPRT1
KRTAP10-3
KRTAP4-2
NIF3L1
NOTCH2NLA
NTAQ1
NUDT18
PLEKHF2
POT1
PRKACA
RPSA
SDCBP
SNRNP200
SRD5A2
TERF1
TERF2
TERF2IP
TINF2
TRIM35
ZNF337
2 interacting genes:
GMCL1
GNMT
Entrez ID
27232
729447
HPRD ID
05970
19674
Ensembl ID
ENSG00000124713
ENSG00000189064
Uniprot IDs
A0A0S2Z5F2
Q14749
V9HW60
Q6NT46
PDB IDs
1R74
2AZT
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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