PRPF8 and ZNF830

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		PRPF8	ZNF830
Description		pre-mRNA processing factor 8	zinc finger protein 830
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm U5 SnRNP Membrane Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 1 Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Spliceosomal Complex Chromosome Nuclear Speck
	Molecular Function	RNA Binding Protein Binding Metallopeptidase Activity U6 SnRNA Binding U1 SnRNA Binding U2 SnRNA Binding U5 SnRNA Binding Isopeptidase Activity K63-linked Polyubiquitin Modification-dependent Protein Binding Pre-mRNA Intronic Binding	Nucleic Acid Binding Protein Binding Zinc Ion Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing Proteolysis RNA Splicing Cellular Response To Lipopolysaccharide Cellular Response To Tumor Necrosis Factor	Ovarian Follicle Development Preantral Ovarian Follicle Growth Blastocyst Growth Transcription-coupled Nucleotide-excision Repair MRNA Processing RNA Splicing Nuclear DNA Replication Mitotic DNA Replication Checkpoint Negative Regulation Of Apoptotic Process Mitotic DNA Damage Checkpoint Replication Fork Protection Chromosome Organization Cell Division Intestinal Epithelial Structure Maintenance
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway	Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER
Drugs
Diseases		Retinitis pigmentosa (RP)
GWAS		Blood protein levels ( 28240269) Calcium levels ( 20705733) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Ischemic stroke ( 29531354) Stroke ( 29531354)	Night sleep phenotypes ( 27126917)
Interacting Genes		21 interacting genes: ABCA1 DHX9 DUX4 ERG GPKOW H2BC5 HNRNPH2 NEDD4 PIN1 PRPF19 PTEN RNF20 SERPINB2 SLC22A2 SND1 SNRNP200 SUMO2 TP53 UBC UBE2I ZNF830	7 interacting genes: FRA10AC1 ILF3 PCBP1 PRPF8 RAB4A SESTD1 THOC5
Entrez ID		10594	91603
HPRD ID		06295	14469
Ensembl ID		ENSG00000174231	ENSG00000198783
Uniprot IDs		Q6P2Q9	Q96NB3
PDB IDs		3E9L 3ENB 3JCR 3LRU 4JK7 4JK8 4JK9 4JKA 4JKB 4JKC 4JKD 4JKE 4JKF 4JKG 4JKH 4KIT 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6S8Q 6S9I 6ZYM 7A5P
Enriched GO Terms of Interacting Partners?
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