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ABL2 and TRIP10
Data Source:
BioGRID
(two hybrid)
ABL2
TRIP10
Description
ABL proto-oncogene 2, non-receptor tyrosine kinase
thyroid hormone receptor interactor 10
Image
GO Annotations
Cellular Component
Cytosol
Actin Cytoskeleton
Phagocytic Cup
Nucleoplasm
Cytoplasm
Lysosome
Golgi Apparatus
Cytosol
Cytoskeleton
Cell Cortex
Cell Projection
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Molecular Function
Magnesium Ion Binding
Phosphotyrosine Residue Binding
Actin Monomer Binding
Protein Kinase Activity
Protein Tyrosine Kinase Activity
Non-membrane Spanning Protein Tyrosine Kinase Activity
Protein Binding
ATP Binding
Manganese Ion Binding
Actin Filament Binding
Protein Binding
Lipid Binding
Identical Protein Binding
Biological Process
Cellular Protein Modification Process
Cell Adhesion
Signal Transduction
Positive Regulation Of Cytosolic Calcium Ion Concentration
Regulation Of Autophagy
Positive Regulation Of Phospholipase C Activity
Positive Regulation Of Neuron Projection Development
Peptidyl-tyrosine Phosphorylation
Regulation Of Endocytosis
Regulation Of Cell Adhesion
Negative Regulation Of Rho Protein Signal Transduction
Exploration Behavior
Positive Regulation Of Oxidoreductase Activity
Cellular Response To Retinoic Acid
Regulation Of Cell Motility
Regulation Of Actin Cytoskeleton Reorganization
Endocytosis
Cell Communication
Signal Transduction
Actin Cytoskeleton Organization
Regulation Of Small GTPase Mediated Signal Transduction
Membrane Organization
Pathways
Role of ABL in ROBO-SLIT signaling
Role of ABL in ROBO-SLIT signaling
Negative regulation of FLT3
Rho GTPase cycle
Clathrin-mediated endocytosis
Drugs
ATP
Dasatinib
XL228
K-00546
Fostamatinib
Diseases
GWAS
IgE grass sensitization (
22036096
)
Interacting Genes
34 interacting genes:
ABI2
ABL1
AR
BCR
C15orf48
CAT
CRK
DOK1
EGFR
EPHB2
ERBB2
ERBB3
ERBB4
FBXO38
GPX1
GRB2
HCK
KIT
MAP3K10
MDM2
MET
NEDD4
NEDD4L
OIP5
PDGFRB
PIK3R3
PSMA7
RIN1
SIVA1
SORBS2
STAT3
TPD52L1
TRIP10
ZMAT1
41 interacting genes:
ABI1
ABL2
AKAP9
ARHGAP12
ARHGAP17
CDC42
CREBBP
CTNNB1
DNM2
DTX3
HOXC11
HTT
JRK
LYN
MEOX1
MEOX2
NKX2-5
PAX6
PDE6G
POT1
PRKACA
RHOJ
RHOQ
RIN1
RXRA
SF3A2
SH3BP1
SMARCE1
SMURF1
SRC
STAT3
TERF1
THAP1
THRB
TINF2
UTF1
WAS
WASF1
WASL
WBP11
ZBTB7B
Entrez ID
27
9322
HPRD ID
01259
05142
Ensembl ID
ENSG00000143322
ENSG00000125733
Uniprot IDs
P42684
Q15642
W4VSQ9
PDB IDs
2ECD
2KK1
2XYN
3GVU
3HMI
3ULR
4EIH
5NP3
5NP5
2CT4
2EFK
2KE4
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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