CYFIP2 and TCERG1

Data Source:
BioGRID (pull down)

		CYFIP2	TCERG1
Description		cytoplasmic FMR1 interacting protein 2	transcription elongation regulator 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane SCAR Complex Neuron Projection Synapse Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	RNA 7-methylguanosine Cap Binding Protein Binding	RNA Polymerase II Repressing Transcription Factor Binding Transcription Elongation Regulator Activity Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity RNA Binding Protein Binding Identical Protein Binding Ubiquitin-like Protein Conjugating Enzyme Binding RNA Polymerase Binding
	Biological Process	Cell Morphogenesis Apoptotic Process Regulation Of Actin Filament Polymerization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Proteolysis Vascular Endothelial Growth Factor Receptor Signaling Pathway Activation Of Cysteine-type Endopeptidase Activity Cell-cell Adhesion	Negative Regulation Of Transcription By RNA Polymerase II MRNA Processing RNA Splicing Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Asthma ( 31959851 32296059) Daytime sleep phenotypes ( 27126917) FEV1 ( 30804560) Gamma glutamyl transferase levels ( 29403010) Lung function (FEV1/FVC) ( 28166213 30804560) Peak expiratory flow ( 30804560) T-Cell Immunoglobulin and Mucin domain 1 levels ( 32460577)	Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		22 interacting genes: ABI1 ABI3 APBB1 BIRC3 BRK1 DNMBP FMR1 FXR1 FXR2 GAS7 MTDH NCK1 NCKAP1 OXTR PLG PRPF40A SMAD4 TCERG1 WASF1 WASF2 YWHAG ZC3H12A	54 interacting genes: ABI1 AURKA BARD1 CHAF1A CHD3 CPSF6 CYFIP1 CYFIP2 DIAPH1 DIAPH2 DNAJB9 ESR1 EVL FANCA FANCC FMNL1 GRB2 HNRNPH1 HNRNPK HNRNPM HNRNPU HSPA1A HSPA5 HSPA8 HTT JUNB LUC7L NONO NPM1 NUDT21 PCBP1 PIAS4 POLR2A PSPC1 SETDB1 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SRSF1 SUMO2 TPM4 U2AF2 UBE2I WAS WASF2 WBP4 WIPF2 WWOX
Entrez ID		26999	10915
HPRD ID		07556	10393
Ensembl ID		ENSG00000055163	ENSG00000113649
Uniprot IDs		B7Z8N7 E7EVJ5 Q96F07	O14776
PDB IDs			2DK7 2DOD 2DOE 2DOF 2E71 2KIQ 2KIS 2MW9 2MWA 2MWB 2MWD 2MWE 2MWF 2N4R 2N4S 2N4T 2N4U 2N4V 2N4W 2NNT 3HFH 3Q1I 4FQG
Enriched GO Terms of Interacting Partners?
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