TCERG1 and WASF2

Data Source:
BioGRID (pull down)

		TCERG1	WASF2
Description		transcription elongation regulator 1	WASP family member 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck	Ruffle Early Endosome Cytosol Cell-cell Junction Actin Cytoskeleton Basolateral Plasma Membrane Lamellipodium SCAR Complex Protein-containing Complex Synapse Extracellular Exosome
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Transcription Elongation Regulator Activity Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity RNA Binding Protein Binding Identical Protein Binding Ubiquitin-like Protein Conjugating Enzyme Binding RNA Polymerase Binding	Actin Binding Protein Binding SH3 Domain Binding Protein Kinase A Regulatory Subunit Binding Cadherin Binding Protein Kinase A Binding Arp2/3 Complex Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II MRNA Processing RNA Splicing Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Transcription By RNA Polymerase II	Angiogenesis Ameboidal-type Cell Migration Endocytosis Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Lamellipodium Assembly Viral Process Rac Protein Signal Transduction Lamellipodium Assembly Actin Cytoskeleton Organization Actin Filament-based Movement Megakaryocyte Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Stress Fiber Assembly Lamellipodium Morphogenesis Postsynaptic Actin Cytoskeleton Organization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways			Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)	Systolic blood pressure ( 30578418)
Interacting Genes		54 interacting genes: ABI1 AURKA BARD1 CHAF1A CHD3 CPSF6 CYFIP1 CYFIP2 DIAPH1 DIAPH2 DNAJB9 ESR1 EVL FANCA FANCC FMNL1 GRB2 HNRNPH1 HNRNPK HNRNPM HNRNPU HSPA1A HSPA5 HSPA8 HTT JUNB LUC7L NONO NPM1 NUDT21 PCBP1 PIAS4 POLR2A PSPC1 SETDB1 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SRSF1 SUMO2 TPM4 U2AF2 UBE2I WAS WASF2 WBP4 WIPF2 WWOX	23 interacting genes: ABI1 ABI2 ABI3 ABL1 ACTB ACTR2 ACTR3 APBB1 ARPC3 BAIAP2 BTK CDC42 CYFIP2 DOCK1 FYN GAS7 GRB2 ITSN2 NCKAP1 PACSIN1 PRPF40A PSTPIP1 TCERG1
Entrez ID		10915	10163
HPRD ID		10393	05796
Ensembl ID		ENSG00000113649	ENSG00000158195
Uniprot IDs		O14776	Q9Y6W5
PDB IDs		2DK7 2DOD 2DOE 2DOF 2E71 2KIQ 2KIS 2MW9 2MWA 2MWB 2MWD 2MWE 2MWF 2N4R 2N4S 2N4T 2N4U 2N4V 2N4W 2NNT 3HFH 3Q1I 4FQG	2A40
Enriched GO Terms of Interacting Partners?
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