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CYFIP2 and WASF2
Data Source:
HPRD
(in vivo)
CYFIP2
WASF2
Description
cytoplasmic FMR1 interacting protein 2
WASP family member 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Membrane
SCAR Complex
Neuron Projection
Synapse
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Ruffle
Early Endosome
Cytosol
Cell-cell Junction
Actin Cytoskeleton
Basolateral Plasma Membrane
Lamellipodium
SCAR Complex
Protein-containing Complex
Synapse
Extracellular Exosome
Molecular Function
RNA 7-methylguanosine Cap Binding
Protein Binding
Actin Binding
Protein Binding
SH3 Domain Binding
Protein Kinase A Regulatory Subunit Binding
Cadherin Binding
Protein Kinase A Binding
Arp2/3 Complex Binding
Biological Process
Cell Morphogenesis
Apoptotic Process
Regulation Of Actin Filament Polymerization
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Positive Regulation Of Proteolysis
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Activation Of Cysteine-type Endopeptidase Activity
Cell-cell Adhesion
Angiogenesis
Ameboidal-type Cell Migration
Endocytosis
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Lamellipodium Assembly
Viral Process
Rac Protein Signal Transduction
Lamellipodium Assembly
Actin Cytoskeleton Organization
Actin Filament-based Movement
Megakaryocyte Development
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Negative Regulation Of Stress Fiber Assembly
Lamellipodium Morphogenesis
Postsynaptic Actin Cytoskeleton Organization
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
VEGFA-VEGFR2 Pathway
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
VEGFA-VEGFR2 Pathway
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS
Asthma (
31959851
32296059
)
Daytime sleep phenotypes (
27126917
)
FEV1 (
30804560
)
Gamma glutamyl transferase levels (
29403010
)
Lung function (FEV1/FVC) (
28166213
30804560
)
Peak expiratory flow (
30804560
)
T-Cell Immunoglobulin and Mucin domain 1 levels (
32460577
)
Systolic blood pressure (
30578418
)
Interacting Genes
22 interacting genes:
ABI1
ABI3
APBB1
BIRC3
BRK1
DNMBP
FMR1
FXR1
FXR2
GAS7
MTDH
NCK1
NCKAP1
OXTR
PLG
PRPF40A
SMAD4
TCERG1
WASF1
WASF2
YWHAG
ZC3H12A
23 interacting genes:
ABI1
ABI2
ABI3
ABL1
ACTB
ACTR2
ACTR3
APBB1
ARPC3
BAIAP2
BTK
CDC42
CYFIP2
DOCK1
FYN
GAS7
GRB2
ITSN2
NCKAP1
PACSIN1
PRPF40A
PSTPIP1
TCERG1
Entrez ID
26999
10163
HPRD ID
07556
05796
Ensembl ID
ENSG00000055163
ENSG00000158195
Uniprot IDs
B7Z8N7
E7EVJ5
Q96F07
Q9Y6W5
PDB IDs
2A40
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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