CBLIF and SLC13A4

Data Source:
BioGRID (two hybrid)

		CBLIF	SLC13A4
Description		cobalamin binding intrinsic factor	solute carrier family 13 member 4
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endosome Microvillus Apical Plasma Membrane Lysosomal Lumen	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Cobalamin Binding	Protein Binding Sodium:sulfate Symporter Activity
	Biological Process	Cobalt Ion Transport Cobalamin Metabolic Process Cobalamin Transport	Sodium Ion Transport Sulfate Transport Anion Transmembrane Transport Sulfate Transmembrane Transport
Pathways		Cobalamin (Cbl, vitamin B12) transport and metabolism Defective GIF causes intrinsic factor deficiency Defective AMN causes hereditary megaloblastic anemia 1 Defective CUBN causes hereditary megaloblastic anemia 1	Sodium-coupled sulphate, di- and tri-carboxylate transporters
Drugs
Diseases
GWAS			Alcoholic chronic pancreatitis ( 28754779) Diverticular disease ( 30177863)
Interacting Genes		8 interacting genes: CBL CUBN FFAR2 SLC13A4 SLC22A23 SLC7A1 SLC7A14 TMEM237	26 interacting genes: ACKR2 CBLIF CD79A CDS1 CERS4 DEFB108B DERL3 EFNA5 EOGT ERMP1 FCER1G GJA5 GPR152 GPR61 IER3 IGFBP5 MS4A13 OPRD1 OTOP3 SLC35A4 SLC35E4 SLC38A1 SLC41A1 TMEM147 TMEM60 TRARG1
Entrez ID		2694	26266
HPRD ID		02024	10372
Ensembl ID		ENSG00000134812	ENSG00000164707
Uniprot IDs		P27352	Q59HF0 Q9UKG4
PDB IDs		2CKT 2PMV 3KQ4
Enriched GO Terms of Interacting Partners?
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