CBLIF and SLC7A14

Data Source:
BioGRID (two hybrid)

		CBLIF	SLC7A14
Description		cobalamin binding intrinsic factor	solute carrier family 7 member 14
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endosome Microvillus Apical Plasma Membrane Lysosomal Lumen	Nucleoplasm Lysosomal Membrane Cytosol Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Cobalamin Binding	Protein Binding Amino Acid Transmembrane Transporter Activity
	Biological Process	Cobalt Ion Transport Cobalamin Metabolic Process Cobalamin Transport	Amino Acid Transmembrane Transport Amino Acid Transport Negative Regulation Of Phosphatase Activity
Pathways		Cobalamin (Cbl, vitamin B12) transport and metabolism Defective GIF causes intrinsic factor deficiency Defective AMN causes hereditary megaloblastic anemia 1 Defective CUBN causes hereditary megaloblastic anemia 1
Drugs
Diseases
GWAS			Obesity (extreme) ( 30677029) Spontaneous preterm birth without premature rupture of membranes ( 31194736)
Interacting Genes		8 interacting genes: CBL CUBN FFAR2 SLC13A4 SLC22A23 SLC7A1 SLC7A14 TMEM237	47 interacting genes: ACSL5 ADGRE2 AGTRAP AIG1 APOL3 BET1 BNIP1 BNIP2 C1GALT1 CBLIF CCDC167 CCL4L2 CD53 CMTM5 DCBLD2 DERL1 EOGT ERMP1 FAM209A FAM20B FATE1 FCER1G FKBP7 IL10RA LINC00839 LTC4S MFF MGLL MMGT1 NINJ2 NSG1 PLPP6 PRB1 SCARF1 SCD SMCO4 TECR TMEM128 TMEM31 TRARG1 TREX1 UBIAD1 VAMP2 VKORC1 YIPF4 YIPF6 ZFPL1
Entrez ID		2694	57709
HPRD ID		02024	17222
Ensembl ID		ENSG00000134812	ENSG00000013293
Uniprot IDs		P27352	Q8TBB6
PDB IDs		2CKT 2PMV 3KQ4
Enriched GO Terms of Interacting Partners?
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