SLC13A4 and CERS4

Data Source:
BioGRID (two hybrid)

		SLC13A4	CERS4
Description		solute carrier family 13 member 4	ceramide synthase 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Sodium:sulfate Symporter Activity	DNA Binding Protein Binding N-acyltransferase Activity Sphingosine N-acyltransferase Activity
	Biological Process	Sodium Ion Transport Sulfate Transport Anion Transmembrane Transport Sulfate Transmembrane Transport	Sphingolipid Biosynthetic Process Ceramide Biosynthetic Process
Pathways		Sodium-coupled sulphate, di- and tri-carboxylate transporters	Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Diverticular disease ( 30177863)	Mean reticulocyte volume ( 32888494) Metabolite levels ( 31628463) Red cell distribution width ( 32888494) Refractive error ( 32231278) Serum metabolite ratios in chronic kidney disease ( 29545352) Sphingolipid levels ( 26068415) Sphingomyelin levels ( 31551469) Thyroid stimulating hormone levels ( 30367059 32769997) Very long-chain saturated fatty acid levels (fatty acid 24:0) ( 25378659)
Interacting Genes		26 interacting genes: ACKR2 CBLIF CD79A CDS1 CERS4 DEFB108B DERL3 EFNA5 EOGT ERMP1 FCER1G GJA5 GPR152 GPR61 IER3 IGFBP5 MS4A13 OPRD1 OTOP3 SLC35A4 SLC35E4 SLC38A1 SLC41A1 TMEM147 TMEM60 TRARG1	47 interacting genes: C1QL4 CCL4L2 CLEC1A COL4A5 CTXN3 CXCL16 CYB5R3 EMD FATE1 FCER1G FXYD6 FXYD6-FXYD2 GPR151 IER3IP1 IGFBP5 ITGAM JAGN1 LHFPL5 MS4A1 NAT8 NEU1 PLP2 PNLIPRP1 PTPN9 SCAMP5 SCD SERF1A SERF1B SERP2 SLC13A4 SLC29A2 SLC35A1 SLC35F6 SLC7A1 SMIM11A SMIM11B STX7 STX8 TEX264 TMEM119 TMEM176A TMEM254 TMEM72 TOMM6 TSPO2 UPK1B VAMP2
Entrez ID		26266	79603
HPRD ID		10372	13962
Ensembl ID		ENSG00000164707	ENSG00000090661
Uniprot IDs		Q59HF0 Q9UKG4	Q53HF9 Q9HA82
PDB IDs
Enriched GO Terms of Interacting Partners?
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