HAVCR1 and DYNLT1

Data Source:
BioGRID (affinity chromatography technology, pull down)

		HAVCR1	DYNLT1
Description		hepatitis A virus cellular receptor 1	dynein light chain Tctex-type 1
Image
GO Annotations	Cellular Component	Cell Surface Integral Component Of Membrane Motile Cilium	Extracellular Region Mitochondrion Golgi Apparatus Spindle Cytoplasmic Dynein Complex Cytoplasmic Microtubule Lamellipodium Secretory Granule Lumen Neuronal Cell Body Host Cell Axonal Growth Cone Secretory Vesicle Ficolin-1-rich Granule Lumen
	Molecular Function	Virus Receptor Activity Phosphatidylserine Binding	Motor Activity Protein Binding Protein C-terminus Binding Identical Protein Binding
	Biological Process	Phagocytosis, Engulfment Positive Regulation Of Mast Cell Activation Viral Entry Into Host Cell	Establishment Of Mitotic Spindle Orientation Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Dendrite Development Intracellular Transport Of Viral Protein In Host Cell Positive Regulation Of Rac Protein Signal Transduction Negative Regulation Of Mitochondrial Membrane Permeability Regulation Of GTPase Activity Neutrophil Degranulation Viral Entry Into Host Cell Neuron Projection Morphogenesis Negative Regulation Of Neurogenesis Cell Division Regulation Of Cytoskeleton Organization Negative Regulation Of Cell Death Axon Development Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Blood protein levels in cardiovascular risk ( 28369058) Cholesterol, total ( 25961943 20686565) Hypertriglyceridemia ( 23505323) LDL cholesterol ( 19060906 25961943 20686565) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Low density lipoprotein cholesterol levels ( 32154731 29593015) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) T-Cell Immunoglobulin and Mucin domain 1 levels ( 32460577) Total cholesterol levels ( 29403010) Triglyceride levels ( 32154731) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglycerides ( 25961943 20686565)
Interacting Genes		3 interacting genes: DYNLT1 SEMA4A UBQLN4	50 interacting genes: ACOX2 ACTN1 APP ARID4B BAG3 BMPR2 CCDC68 DDX54 DHX33 DNAJA2 DOC2A DOC2B DVL1 DVL2 DYNC1I1 DYNC1I2 DYNLT2B DYNLT3 FXR2 HAVCR1 HSPB7 HSPB9 ILF2 KIF2A KLK15 LNX1 NHSL2 NTAQ1 NUP153 NUP62 OLFM3 PELO PITX2 PSMA1 PTGES3L-AARSD1 PTH2R PVR RAD21 RBM14 RRAGA SDCBP SIRPA SVIL TCEANC TROAP TUBA3C TXN UXT VDAC1 XRN2
Entrez ID		26762	6993
HPRD ID		09404	15987
Ensembl ID		ENSG00000113249	ENSG00000146425
Uniprot IDs		B4DPB1 E9PFX0 Q96D42	P63172
PDB IDs		5DZO 5F70	5JPW
Enriched GO Terms of Interacting Partners?
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