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FAM50B and CARD9
Data Source:
BioGRID
(two hybrid)
FAM50B
CARD9
Description
family with sequence similarity 50 member B
caspase recruitment domain family member 9
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Midbody
Intercellular Bridge
Cytoplasm
Cytosol
Plasma Membrane
Protein-containing Complex
Molecular Function
Protein Binding
Protein Binding
Protein Homodimerization Activity
CARD Domain Binding
Biological Process
Chromatin Organization
Stimulatory C-type Lectin Receptor Signaling Pathway
I-kappaB Kinase/NF-kappaB Signaling
Response To Fungus
Response To Peptidoglycan
Response To Muramyl Dipeptide
Regulation Of Interleukin-2 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Stress-activated MAPK Cascade
Response To Drug
Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Response To Exogenous DsRNA
Innate Immune Response
Positive Regulation Of JNK Cascade
Defense Response To Gram-positive Bacterium
Defense Response To Virus
Pathways
NOD1/2 Signaling Pathway
CLEC7A (Dectin-1) signaling
Drugs
Diseases
Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
GWAS
Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin) (
23648065
)
Acute insulin response (insulin secretion adjusted) (
28490609
)
Ankylosing spondylitis (
23749187
21743469
)
Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) (
26974007
)
Crohn's disease (
28067908
22936669
21102463
)
IgA nephropathy (
25305756
)
Inflammatory bowel disease (
28067908
23128233
)
Joint damage in rheumatoid arthritis (
26498133
)
Large artery stroke (
28265093
)
Monocyte chemoattractant protein-1 levels (
23017229
)
Obesity-related traits (
23251661
)
Pediatric autoimmune diseases (
26301688
)
Ulcerative colitis (
19915572
28067908
20228799
21297633
)
Interacting Genes
49 interacting genes:
ACTN2
ADRA1A
BICD2
CARD9
CCDC136
CCDC57
CCDC85B
CCDC89
CCNC
CDR2
DEUP1
FSD2
GFAP
GMCL1
GOLGA2
GRIPAP1
HAP1
HOOK2
IKZF1
KASH5
KPNA3
KPNA4
KRT31
KRT34
LDOC1
LZTS1
LZTS2
MID1
MID2
MLH1
NUTF2
PAX6
PDE4DIP
PIBF1
PSMB1
RABEP1
TACC1
TBC1D1
TFIP11
TRAF2
TRIM14
TRIM37
TRIM54
UBL5
VAC14
VPS52
WBP4
ZMYND12
ZRANB1
138 interacting genes:
ABLIM1
AMOTL2
AXIN1
BCL10
BLZF1
C1orf94
C2CD6
CABP2
CARD10
CBX8
CCDC13
CCDC136
CCDC85B
CCDC88B
CCHCR1
CDC37
CDCA7L
CDK2AP1
CEP57L1
CEP70
CSNK2A1
CWF19L2
DAXX
DISC1
DUSP13
DVL2
EFHC2
EIF4A3
EIF4E2
FAM124B
FAM161A
FAM161B
FAM50B
FAM90A1
FOXD4L1
GAS8
GEM
HMBOX1
HOXB5
HSF2BP
IHO1
IKZF3
INO80B
IQCE
KANK2
KCTD9
KIAA0408
KIAA1328
KIF9
KIFC3
KRT15
KRT16
KRT19
KRT31
KRT40
KRT75
KRTAP10-1
KRTAP10-3
KRTAP10-5
KRTAP5-7
L3MBTL2
LENG1
LMO1
LMO3
LNX1
LZTS1
LZTS2
MCRS1
MEOX2
MFAP1
MID2
MYO15B
NECAB2
NTAQ1
PAK5
PBX2
PHC2
PIBF1
PICK1
PKP2
PNMA5
PPP1R18
PRPF18
PSMA4
RBAK
RTP5
SAXO1
SCNM1
SHISA6
SLAIN1
SSX2IP
STMN3
STX11
SUMO1
TASOR2
TCEANC
TCL1A
TEX33
TFIP11
TLE5
TNFAIP1
TNS4
TRIM14
TRIM23
TRIM29
TRIM42
TRIM54
TRIM62
TSGA10IP
TSNAX
UBE2I
UNKL
USH1G
USP15
USP2
VCPKMT
VPS28
YES1
ZBTB16
ZC2HC1C
ZCCHC7
ZGPAT
ZMYM5
ZNF121
ZNF19
ZNF20
ZNF250
ZNF417
ZNF426
ZNF572
ZNF587
ZNF620
ZNF655
ZNF688
ZNF774
ZNF829
ZRANB1
ZZZ3
Entrez ID
26240
64170
HPRD ID
16883
06236
Ensembl ID
ENSG00000145945
ENSG00000187796
Uniprot IDs
A0A024QZY3
Q9Y247
A0A024R8F1
Q9H257
PDB IDs
6E25
6E26
6E27
6E28
6N2M
6N2P
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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