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AGO1 and KHDRBS1
Data Source:
BioGRID
(two hybrid)
AGO1
KHDRBS1
Description
argonaute RISC component 1
KH RNA binding domain containing, signal transduction associated 1
Image
GO Annotations
Cellular Component
P-body
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Polysome
RISC Complex
Cytoplasmic Ribonucleoprotein Granule
RISC-loading Complex
Ribonucleoprotein Complex
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Protein-containing Complex
Grb2-Sos Complex
Molecular Function
RNA Polymerase II Complex Binding
Core Promoter Sequence-specific DNA Binding
RNA Binding
Double-stranded RNA Binding
Single-stranded RNA Binding
Endoribonuclease Activity
Protein Binding
MiRNA Binding
DNA Binding
RNA Binding
MRNA Binding
Protein Binding
Poly(A) Binding
Poly(U) RNA Binding
SH3 Domain Binding
Protein Domain Specific Binding
Signaling Adaptor Activity
SH2 Domain Binding
Identical Protein Binding
Protein-containing Complex Binding
Protein Tyrosine Kinase Binding
Biological Process
Nuclear-transcribed MRNA Catabolic Process
Wnt Signaling Pathway, Calcium Modulating Pathway
RNA Secondary Structure Unwinding
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Negative Regulation Of Angiogenesis
Pre-miRNA Processing
Post-transcriptional Gene Silencing By RNA
Production Of MiRNAs Involved In Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
MRNA Cleavage Involved In Gene Silencing By MiRNA
MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA
Regulation Of Megakaryocyte Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Gene Silencing By MiRNA
RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
MRNA Cleavage Involved In Gene Silencing By SiRNA
G1/S Transition Of Mitotic Cell Cycle
G2/M Transition Of Mitotic Cell Cycle
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Alternative MRNA Splicing, Via Spliceosome
MRNA Processing
Spermatogenesis
Regulation Of Protein Stability
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Translational Initiation
Regulation Of RNA Export From Nucleus
Positive Regulation Of RNA Export From Nucleus
Regulation Of MRNA Splicing, Via Spliceosome
T Cell Receptor Signaling Pathway
Pathways
Pre-NOTCH Transcription and Translation
MicroRNA (miRNA) biogenesis
Oxidative Stress Induced Senescence
Oncogene Induced Senescence
Ca2+ pathway
Small interfering RNA (siRNA) biogenesis
Post-transcriptional silencing by small RNAs
Transcriptional regulation by small RNAs
TP53 Regulates Metabolic Genes
MAPK6/MAPK4 signaling
Transcriptional Regulation by VENTX
Regulation of RUNX1 Expression and Activity
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Regulation of PTEN mRNA translation
Competing endogenous RNAs (ceRNAs) regulate PTEN translation
Transcriptional Regulation by MECP2
Transcriptional Regulation by MECP2
Estrogen-dependent gene expression
Regulation of MECP2 expression and activity
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
PTK6 Regulates Proteins Involved in RNA Processing
Drugs
Diseases
GWAS
Body mass index (
26426971
)
Interacting Genes
8 interacting genes:
AGO2
APP
DCP1A
DCP2
DICER1
KHDRBS1
PRNP
RELA
110 interacting genes:
ABI2
ACTB
AGO1
AHI1
AMPH
APBB1
ARHGEF4
ARHGEF9
AZIN1
BAIAP2L1
BTK
CBL
CD2AP
CDC42
CDK1
CIRBP
CLK1
CREB3L3
CREBBP
CRK
CRKL
CSK
DDX5
DHX9
DLG1
DLG2
DLG3
DLG4
DNMBP
DOCK2
DOCK3
EFEMP1
EMG1
FGR
FNBP4
FRK
FYN
GAS7
GPHN
GRAP
GRAP2
GRB2
HCK
HNRNPK
INSR
ITK
ITPRID2
ITSN1
ITSN2
JAK3
KHDRBS3
LCK
LYN
MAPK1
MYO1C
MYO7A
NCF1
NCK1
NCK2
NCKIPSD
NPHP1
OSTF1
PACSIN1
PALS2
PIK3R1
PIK3R3
PLCG1
PLCG2
POT1
PPP1R13B
PRMT1
PSTPIP1
PTBP2
PTK6
PTPN6
RALY
RAPSN
RASA1
RBFOX2
RBM7
RBMX
RUSC2
SASH1
SCG5
SH3PXD2A
SH3YL1
SKAP2
SMAD2
SMARCA2
SNX30
SNX9
SORBS1
SPATA13
SRC
SRPK2
STAT3
STUB1
TBL1X
TJP1
TSPOAP1
TUBB3
UBA52
UBASH3B
UBC
VAV1
WBP4
YES1
YTHDC1
ZBTB7A
ZDHHC6
Entrez ID
26523
10657
HPRD ID
06942
03926
Ensembl ID
ENSG00000092847
ENSG00000121774
Uniprot IDs
A0A6I8PTZ8
B2RAD8
B3KME0
Q5TA58
Q9UL18
Q07666
PDB IDs
1SI2
1SI3
4KRE
4KRF
4KXT
5W6V
2XA6
3QHE
Enriched GO Terms of Interacting Partners
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