KHDRBS1 and MYO1C

Data Source:
BioGRID (unspecified method)

		KHDRBS1	MYO1C
Description		KH RNA binding domain containing, signal transduction associated 1	myosin IC
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Protein-containing Complex Grb2-Sos Complex	Stress Fiber Nuclear Pore Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Microvillus Brush Border Basal Plasma Membrane Actin Cytoskeleton Membrane Lateral Plasma Membrane Unconventional Myosin Complex Nuclear Body Cytoplasmic Vesicle Membrane Filamentous Actin Vesicle Ruffle Membrane Membrane Raft Phagocytic Vesicle Stereocilium Membrane Extracellular Exosome
	Molecular Function	DNA Binding RNA Binding MRNA Binding Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding Protein Domain Specific Binding Signaling Adaptor Activity SH2 Domain Binding Identical Protein Binding Protein-containing Complex Binding Protein Tyrosine Kinase Binding	Microfilament Motor Activity Signaling Receptor Binding Protein Binding Calmodulin Binding ATP Binding Protein C-terminus Binding Actin-dependent ATPase Activity Small GTPase Binding Actin Filament Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Spermatogenesis Regulation Of Protein Stability Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Translational Initiation Regulation Of RNA Export From Nucleus Positive Regulation Of RNA Export From Nucleus Regulation Of MRNA Splicing, Via Spliceosome T Cell Receptor Signaling Pathway	Protein Targeting Protein Targeting To Membrane Actin Filament Organization Vesicle Transport Along Actin Filament Positive Regulation Of Cell Migration Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Gene Expression, Epigenetic MRNA Transport Cellular Response To Interferon-gamma Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Cellular Response To Insulin Stimulus Positive Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Regulation Of Bicellular Tight Junction Assembly
Pathways		PTK6 Regulates Proteins Involved in RNA Processing	Translocation of SLC2A4 (GLUT4) to the plasma membrane Regulation of actin dynamics for phagocytic cup formation FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Appendicular lean mass ( 33097823) Atrial fibrillation ( 30061737) Mean platelet volume ( 32888494) Neutrophil count ( 32888494) Pulse pressure ( 30578418) White blood cell count ( 32888494)
Interacting Genes		110 interacting genes: ABI2 ACTB AGO1 AHI1 AMPH APBB1 ARHGEF4 ARHGEF9 AZIN1 BAIAP2L1 BTK CBL CD2AP CDC42 CDK1 CIRBP CLK1 CREB3L3 CREBBP CRK CRKL CSK DDX5 DHX9 DLG1 DLG2 DLG3 DLG4 DNMBP DOCK2 DOCK3 EFEMP1 EMG1 FGR FNBP4 FRK FYN GAS7 GPHN GRAP GRAP2 GRB2 HCK HNRNPK INSR ITK ITPRID2 ITSN1 ITSN2 JAK3 KHDRBS3 LCK LYN MAPK1 MYO1C MYO7A NCF1 NCK1 NCK2 NCKIPSD NPHP1 OSTF1 PACSIN1 PALS2 PIK3R1 PIK3R3 PLCG1 PLCG2 POT1 PPP1R13B PRMT1 PSTPIP1 PTBP2 PTK6 PTPN6 RALY RAPSN RASA1 RBFOX2 RBM7 RBMX RUSC2 SASH1 SCG5 SH3PXD2A SH3YL1 SKAP2 SMAD2 SMARCA2 SNX30 SNX9 SORBS1 SPATA13 SRC SRPK2 STAT3 STUB1 TBL1X TJP1 TSPOAP1 TUBB3 UBA52 UBASH3B UBC VAV1 WBP4 YES1 YTHDC1 ZBTB7A ZDHHC6	6 interacting genes: BAZ1B CBL CDC42 KHDRBS1 PTEN RRN3
Entrez ID		10657	4641
HPRD ID		03926	09411
Ensembl ID		ENSG00000121774	ENSG00000197879
Uniprot IDs		Q07666	O00159
PDB IDs		2XA6 3QHE	4BYF
Enriched GO Terms of Interacting Partners?
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