FBXL3 and MSRA

Data Source:
BioGRID (two hybrid)

		FBXL3	MSRA
Description		F-box and leucine rich repeat protein 3	methionine sulfoxide reductase A
Image			No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Cytosol Nuclear Body SCF Ubiquitin Ligase Complex	Nucleoplasm Cytoplasm Mitochondrion Cytosol Plasma Membrane Actin Cytoskeleton Extracellular Exosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding	Protein Binding Peptide-methionine (S)-S-oxide Reductase Activity L-methionine-(S)-S-oxide Reductase Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Protein Polyubiquitination Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Destabilization Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Post-translational Protein Modification Rhythmic Process Regulation Of Cell Cycle	Cellular Protein Modification Process Methionine Metabolic Process Response To Oxidative Stress Protein Repair Cellular Response To Oxidative Stress
Pathways		Association of TriC/CCT with target proteins during biosynthesis Circadian Clock Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Protein repair
Drugs			1,4-Dithiothreitol
Diseases
GWAS		Chronotype ( 30696823) Metabolite levels ( 23823483) Morning person ( 30696823) Morning vs. evening chronotype ( 26835600) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)	Adiposity ( 19557161) Adult body size ( 32376654) Age at first sexual intercourse ( 27089180) Alzheimer's disease ( 20452100) Asthma-chronic obstructive pulmonary disease overlap syndrome ( 30657218) Autoimmune thyroid disease ( 32581359) Barrett's esophagus ( 27527254) Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Bipolar disorder ( 31043756) Bipolar disorder and schizophrenia ( 22688191) Body mass index ( 30108283 31453325) Body mass index variance ( 31453325) Body size at age 10 ( 32376654) Brain morphology (MOSTest) ( 32665545) Bulimia nervosa ( 23568457) Chronotype ( 26835600) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cooked vegetable consumption ( 32066663) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Estimated glomerular filtration rate ( 31152163) Feeling worry ( 29500382) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) General factor of neuroticism ( 30867560) General risk tolerance (MTAG) ( 30643258) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) HDL cholesterol levels ( 32203549) Hypertension ( 19430479) Insomnia ( 32332799) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Irritable mood ( 29500382) Joint mobility (Beighton score) ( 27182965) Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (diuretics) ( 31015401) Medication use (thyroid preparations) ( 31015401) Myopia (pathological) ( 23049088) Neurociticism ( 29500382) Nose size ( 27182965) Obesity (early onset extreme) ( 20421936) Oily fish consumption ( 32066663) Plasma kynurenine to tryptophan ratio in major depressive disorder ( 29317604) Pork consumption ( 32066663) Processed meat consumption ( 32066663) Pulse pressure ( 30578418) Pulse pressure x alcohol consumption interaction (2df test) ( 29912962) Raw vegetable consumption ( 32066663) Refractive error ( 32231278) Remission after SSRI treatment in MDD or neuroticism ( 29559929) Response to chemotherapy in breast cancer hypertensive cases (cumulative dose) (bevacizumab) ( 25117820) Schizophrenia ( 28991256 21679298 30285260 26198764) Smoking initiation (ever regular vs never regular) ( 30679032) Systemic lupus erythematosus ( 28714469) Systolic blood pressure ( 30224653 30578418) Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) TPE interval (resting) ( 32386560) Triglyceride levels ( 32203549) Type 2 diabetes ( 30297969) Waist circumference ( 30108283) Weight ( 30108283)
Interacting Genes		7 interacting genes: CDC34 CEP57 CRY1 MSRA PICK1 SKP1 UBE2D2	6 interacting genes: CTNNA3 EFCAB11 FBXL3 HPCAL4 P4HA3 SELENBP1
Entrez ID		26224	4482
HPRD ID		05737	03152
Ensembl ID		ENSG00000005812	ENSG00000175806
Uniprot IDs		Q9UKT7	Q9UJ68
PDB IDs		4I6J
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?