IPCEF1 and CYTH3

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		IPCEF1	CYTH3
Description		interaction protein for cytohesin exchange factors 1	cytohesin 3
Image
GO Annotations	Cellular Component	Cytosol Plasma Membrane	Golgi Membrane Ruffle Nucleoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
	Molecular Function	Peroxidase Activity Oxygen Carrier Activity Protein Binding Protein Domain Specific Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding
	Biological Process	Response To Oxidative Stress Oxygen Transport Cellular Oxidant Detoxification	Regulation Of ARF Protein Signal Transduction Positive Regulation Of Cell Adhesion Golgi Vesicle Transport Regulation Of Catalytic Activity Establishment Of Epithelial Cell Polarity
Pathways			Intra-Golgi traffic
Drugs			Inositol 1,3,4,5-Tetrakisphosphate Inositol-(1,3,4,5,6)-Pentakisphosphate
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29679657) Arterial stiffness index ( 31235810) Asthma (childhood onset) ( 27611488) Chronic lymphocytic leukemia ( 28165464 24292274) Chronotype (sMEQ score) ( 32579418)	Asthma ( 27611488) Body mass index ( 26426971) Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321)
Interacting Genes		5 interacting genes: CEP70 CYTH1 CYTH2 CYTH3 CYTH4	12 interacting genes: ARFIP2 CALCOCO1 CCDC120 CNKSR1 CYTIP FRMD4B IFI35 INAVA IPCEF1 PIK3CA SYCE1 TAMALIN
Entrez ID		26034	9265
HPRD ID		17851	05469
Ensembl ID		ENSG00000074706	ENSG00000008256
Uniprot IDs		Q8WWN9	O43739
PDB IDs		5MR1	4KAX 6U3E 6U3G
Enriched GO Terms of Interacting Partners?
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