PTPN23 and CEP55

Data Source:
BioGRID (two hybrid)

		PTPN23	CEP55
Description		protein tyrosine phosphatase non-receptor type 23	centrosomal protein 55
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endosome Early Endosome Cytosol Nuclear Body Ciliary Basal Body Intracellular Membrane-bounded Organelle Extracellular Exosome	Cytoplasm Centrosome Centriole Plasma Membrane Membrane Midbody Cleavage Furrow Centriolar Satellite Intercellular Bridge Flemming Body
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Protein Kinase Binding	Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Epithelial Cell Migration Protein Transport Endocytic Recycling Peptidyl-tyrosine Dephosphorylation Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Early Endosome To Late Endosome Transport Cilium Assembly Positive Regulation Of Wnt Protein Secretion Cellular Response To Cytokine Stimulus Positive Regulation Of Homophilic Cell Adhesion Positive Regulation Of Adherens Junction Organization Positive Regulation Of Early Endosome To Late Endosome Transport	Mitotic Cytokinesis Nucleus Organization Mitotic Metaphase Plate Congression Multicellular Organism Development Regulation Of Phosphatidylinositol 3-kinase Signaling Establishment Of Protein Localization Midbody Abscission Cranial Skeletal System Development
Pathways		Interleukin-37 signaling
Drugs
Diseases
GWAS		C-reactive protein levels ( 30388399) Refractive error ( 32231278) Type 2 diabetes (adjusted for BMI) ( 29632382)	High density lipoprotein cholesterol levels ( 30498476) Metabolite levels ( 23823483)
Interacting Genes		11 interacting genes: ALG2 CEP19 CEP55 CHMP4B DDX24 LRRK2 NOTCH2NLA PSMA3 TRIM27 UBAP1 UBC	77 interacting genes: AKAP9 ANXA11 ARHGEF15 C1orf109 C1orf216 CBY2 CCBE1 CCDC120 CCHCR1 CDC37 CDC45 CDK1 CDSN CEP57L1 COL8A1 DTNB ECSIT EIF1AD ENKD1 FAM161B FAM90A1 FBF1 FXR2 GOLGA2 GOLGA8DP HAUS1 HGS HSF2BP KANK2 KIFC3 LGALS4 LRRC23 MAPK1 MAPK1IP1L MFAP1 MIA3 MORF4L2 NDEL1 NOS3 NTAQ1 PCNT PDCD6IP PEF1 PIN1 PLEKHG6 PLK1 POLM POM121 PPP1R16B PSEN2 PSMC2 PTPN23 PWWP3A RAB3D RBM14 RBM17 RBM22 RCOR3 RNF32 SDCBP SNRPB SNW1 SS18L1 SUPT5H TCL1A TEAD4 TEX11 TEX14 TFG TP53BP2 TSG101 UBC VPS37C VPS37D WASHC1 WASHC3 ZNF48
Entrez ID		25930	55165
HPRD ID		05959	12569
Ensembl ID		ENSG00000076201	ENSG00000138180
Uniprot IDs		B4DST5 Q9H3S7	Q53EZ4
PDB IDs		3RAU 5CRU 5CRV 5LM1 5LM2 5MJY 5MJZ 5MK0 5MK1 5MK2 5MK3	3E1R 3WUT 3WUU 3WUV
Enriched GO Terms of Interacting Partners?
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