CEP55 and VPS37D

Data Source:
BioGRID (two hybrid)
HPRD (in vitro)

		CEP55	VPS37D
Description		centrosomal protein 55	VPS37D subunit of ESCRT-I
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Plasma Membrane Membrane Midbody Cleavage Furrow Centriolar Satellite Intercellular Bridge Flemming Body	ESCRT I Complex Endosome Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle Host Cell Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Mitotic Cytokinesis Nucleus Organization Mitotic Metaphase Plate Congression Multicellular Organism Development Regulation Of Phosphatidylinositol 3-kinase Signaling Establishment Of Protein Localization Midbody Abscission Cranial Skeletal System Development	Protein Targeting To Membrane Protein Targeting To Vacuole Endosomal Transport Macroautophagy Viral Life Cycle Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Intracellular Transport Of Virus
Pathways			Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs
Diseases
GWAS		High density lipoprotein cholesterol levels ( 30498476) Metabolite levels ( 23823483)	Coffee consumption (cups per day) ( 25288136) Gamma glutamyl transferase levels ( 29403010) Hypertriglyceridemia ( 23505323) Malaria ( 31844061) Serum albumin level ( 29403010) Serum uric acid levels ( 29403010)
Interacting Genes		77 interacting genes: AKAP9 ANXA11 ARHGEF15 C1orf109 C1orf216 CBY2 CCBE1 CCDC120 CCHCR1 CDC37 CDC45 CDK1 CDSN CEP57L1 COL8A1 DTNB ECSIT EIF1AD ENKD1 FAM161B FAM90A1 FBF1 FXR2 GOLGA2 GOLGA8DP HAUS1 HGS HSF2BP KANK2 KIFC3 LGALS4 LRRC23 MAPK1 MAPK1IP1L MFAP1 MIA3 MORF4L2 NDEL1 NOS3 NTAQ1 PCNT PDCD6IP PEF1 PIN1 PLEKHG6 PLK1 POLM POM121 PPP1R16B PSEN2 PSMC2 PTPN23 PWWP3A RAB3D RBM14 RBM17 RBM22 RCOR3 RNF32 SDCBP SNRPB SNW1 SS18L1 SUPT5H TCL1A TEAD4 TEX11 TEX14 TFG TP53BP2 TSG101 UBC VPS37C VPS37D WASHC1 WASHC3 ZNF48	4 interacting genes: ARMC7 CEP55 HGS TSG101
Entrez ID		55165	155382
HPRD ID		12569	19106
Ensembl ID		ENSG00000138180	ENSG00000176428
Uniprot IDs		Q53EZ4	Q86XT2
PDB IDs		3E1R 3WUT 3WUU 3WUV
Enriched GO Terms of Interacting Partners?
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